Numéro CAS : 121-14-2

Identification

Description


Numéro UN : UN2038

Formule moléculaire brute : C7H6N2O4

Principaux synonymes

Noms français :

  • 2,4-Dinitrotoluene
  • BENZENE, 1-METHYL-2,4-DINITRO-
  • DINITRO-2,4 TOLUENE
  • Dinitro-2,4 toluène

Noms anglais :

  • 2,4-Dinitrotoluene
Utilisation et sources d'émission

Fabrication de produits organiques, fabrication d'explosifs

Références

  • ▲1.  Cairelli, S.G., Ludwig, H.R. et Whalen, J.J., Documentation for immediately dangerous to life or health concentrations (IDLHS). Cincinnati (OH) : NIOSH. (1994). PB-94-195047. [RM-515102]   http://www.cdc.gov/niosh/idlh/intridl4.html
  • ▲2.  National Fire Protection Association, Fire protection guide to hazardous materials. 14th ed. Quincy, Mass. : NFPA. (2010). [RR-334001]
  • ▲3.  American Conference of Governmental Industrial Hygienists, Documentation of the threshold limit values and biological exposure indices / Documentation of TLV's and BEI's. 7th ed. Cincinnati, Ohio : ACGIH. (2001-). Publication #0100Doc. [RM-514008]   http://www.acgih.org
  • ▲4.  American Conference of Governmental Industrial Hygienists, Documentation of the threshold limit values and biological exposure indices / Documentation of TLV's and BEI's. 6th ed. Cincinnati, Ohio : ACGIH. (1991-2000). Publication 0206. [RM-514008]   http://www.acgih.org
  • ▲5.  IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, Printing processes and printing inks, carbon black and some nitro compounds. IARC monographs on the evaluation of carcinogenic risks to humans, Vol. 65. Lyon : International Agency for Research on Cancer. (1996). [MO-018684]   https://monographs.iarc.fr/wp-content/uploads/2018/06/mono65.pdf
  • ▲5.  IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, Printing processes and printing inks, carbon black and some nitro compounds. IARC monographs on the evaluation of carcinogenic risks to humans, Vol. 65. Lyon : International Agency for Research on Cancer. (1996). [MO-018684]   https://monographs.iarc.fr/wp-content/uploads/2018/06/mono65.pdf
  • ▲6.  Mirsalis, J.C., Tyson, C.K. et Butterworth, B.E., «Detection of genotoxic carcinogens in the in vivo-in vitro hepatocyte DNA repair assay.» Environmental Mutagenesis. Vol. 4, p. 553-562. (1982). [AP-016624]
  • ▲7.  Canada. Ministère des transports, Règlement sur le transport des marchandises dangereuses. Ottawa : Éditions du gouvernement du Canada. (2014). [RJ-410222]   http://www.tc.gc.ca/fra/tmd/clair-menu-497.htm
    http://www.tc.gc.ca/tmd/menu.htm

Autres sources d'information

  • National Institute for Occupational Safety and Health, NIOSH pocket guide to chemical hazards. 3 ed. Cincinnati, Ohio : NIOSH. (2007). [RM-514001]   https://www.cdc.gov/niosh/npg/default.html
  • American Conference of Governmental Industrial Hygienists, 2022 TLVs and BEIs with 7th edition documentation CD-ROM. Cincinnati, OH : ACGIH. (2022). Publication 0111CD. [CD-120061]   http://www.acgih.org
  • Lenga, R.E., The Sigma-Aldrich library of chemical safety data. 2nd ed. Milwaukee : Sigma-Aldrich. (1988).
  • Sax, N.I., Dangerous properties of industrial materials. 7th ed. Toronto : Van Nostrand Reinhold. (1989). [RR-014005]
  • Bioassay of 2-4-dinitrotoluene for possible carcinogenicity. Springfield, VA : NTIS. (1978). PB: 280 990. [MO-001580]
  • Leonard, T.B. , Lyght, O. et Popp, J.A. , «Dinitrotoluene structure-dependant initiation of hepatocytes in vivo.» Carcinogenesis. Vol. 4, no. 8, p. 1059-1061. (1983). [AP-012852]
  • Kedderis, G.L. , Dyroff, M.C. et Rickert, D.E. , «Hepatic macromolecular covalent binding of the hepatocarcinogen 2,6-dinitrotoluene and its 2,4-isomer in vivo: modulation by the sulfotransfera inhibitors pentachlorophenol and 2,6-dichloro-4-nitrophenol.» Carcinogenesis. Vol. 5, no. 9, p. 1199-1204. (1984). [AP-012850]
  • Ellis, H.V. et al., «Subchronic and chronic toxicity studies of 2,4-dinitrotoluene. Part 1. Beagle dogs.» Journal of the American College of Toxicology. Vol. 4, no. 5, p. 233-242. (1985). [AP-044588]
  • Rickert, D.E. , Schnell, S.R. et Long, R.M. , «Hepatic macromolecular covalent binding and intestinal disposition of (14C) dinitrotoluenes.» Journal of Toxicology and Environmental Health. Vol. 11, p. 555-567. (1983). [AP-019262]
  • Leonard, T.B. , Lyght, O. et Popp, J.A. , «Structure-specific dinitrotoluene (DNT) promotion on initiated hepatocytes.» Proceedings of the National Academy of Sciences of the U.S.A.. Vol. 123, no. 399, p. 101. (1982). [AP-021574]
  • Toxicologic Pathology, VOL. 10, NO. 2, 1982, P. 190-194 [AP-O05063]
  • Schut, H.A. , Loeb, T.R. et Stoner, G.D. , «Distribution, elimination and test for carcinogenicity of 2,4-dinitrotoluene in strain A mice .» Toxicology and Applied Pharmacology. Vol. 64, p. 213-220. (1982). [AP-012846]
  • Bloch, E. et al., «Reproductive toxicity of 2,4-dinitrotoluene in the rat.» Toxicology and Applied Pharmacology. Vol. 94, p. 466-472. (1988). [AP-037197]
  • Reader, S.C.J. et Foster, P.D.M., «The in vitro effects of four isomers of dinitrotoluene on rat Sertoli-germ cell cocultures: germ cell detachment and lactate and pyruvate production.» Toxicology and Applied Pharmacology. Vol. 106, p. 287-294. (1990). [AP-037198]
  • AMERICAN JOURNAL OF DIGESTIVE DISEASES, VOL. 9, NO. 10, 1942 [AP-037236]
  • Vernot, E.H. et al., «Acute toxicity and skin corrosion data for some organic and inorganic compounds and aqueous solutions.» Toxicology and Applied Pharmacology. Vol. 42, p. 417-423. (1977). [AP-000468]
  • Dinitrotoluenes (DNT). NIOSH current intelligence bulletin; 44 . Cincinnati, Oh : NIOSH. (1985). NIOSH: 85-109. [MO-005637]
  • Dowgerty, R.W., Lane, R.W., Simon, G.S., Reproductive toxicity and lack of dominant lethal effects of 2,4-dinitrotoluene in the male rat., 1985 Microfiche : PB86-208766, EPA/600/J-85/413
  • Etnier, E.L., Water quality criteria for 2,4-dinitrololuene and 2,6-dinitrololuene: Final report. USA : Oak Ridge National Lab. (1987). Microfiche : ORNL-6312 E 1.99, DE88 000985
  • Knudsen, J.J., Makovec, G.T. et Mcgown, E.L., Fourteen-day feeding study of 2,4-dinitrotoluene in male and female rats.. San Francisco : Letterman Army Institute. (1983). Microfiche : AD-A126 069, LAIR-138
  • Smith, K.N., Determination of the reproductive effects in mice of nine selected chemicals., 1983 Microfiche : PB84-183540
  • Agency for Toxic Substances and Disease Registry, Toxicological profile for 2,4-dinitrotoluene and 2,6-dinitrotoluene. Atlanta, GA : ATSDR. (1989). Draft for public comment. Microfiche : PB90-171430, ATSDR/TP-89/13   http://www.atsdr.cdc.gov/toxprofiles/
  • Brower, M.E., Hartley, W.R., Roberts, W.C., Health advisory for 2,4-dinitrotoluene and 2,6-dinitrotoluene (dnt) (final report)., 1992 Microfiche : PB92-189315
  • Ellis, H.V. et al., Mammalian toxicity of munitions compounds phase III : Effects of life-time exposure part I : 2,4-Dinitrotoluene. Final report no 7. Kansas City : Midwest Research Institute. (1979). [MO-016944], Microfiche : AD-A077 692

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