Hydroxyanisole butylé (BHA)

Numéro CAS : 25013-16-5

Identification

Description


Formule moléculaire brute : C11H16O2

Principaux synonymes

Noms français :

  • (1,1-DIMETHYLETHYL)-4-METHOXYPHENOL
  • 2-TERT-BUTYL-4-METHOXYPHENOL
  • 3-tert-butyl-4-methoxyphenol
  • Butyl hydroxyanisole
  • BUTYLE METHOXY-4 PHENOL (TERT-)
  • Hydroxy anisole butylé
  • Hydroxyanisole butylé
  • PHENOL, (1,1-DIMETHYLETHYL)-4-METHOXY-
  • PHENOL, TERT-BUTYL-4-METHOXY-
  • TERT-BUTYL-4-HYDROXYANISOLE
  • TERT-BUTYL-4-METHOXYPHENOL
  • TERT-BUTYL-4-METHYLPHENOL
  • TERT-BUTYL-PARA-HYDROXYANISOLE
  • TERT-BUTYLHYDROXYANISOLE

Noms anglais :

  • Anisole, butylated hydroxy-
  • Butylated hydroxyanisole
Commentaires 1 2 3 4 5

Le produit commercial est généralement un mélange de deux isomères, le 2-tert-butyl-4-méthoxyphénol et le 3-tert-butyl-4-méthoxyphénol.

Utilisation et sources d'émission

Additif alimentaire, additif cosmétique

Références

  • ▲1.  O’Neil, M.J., Smith, A. et Heckelman, P.E., The Merck index : an encyclopedia of chemicals, drugs, and biologicals. 13th ed. Cambridge, MA : Cambridge Soft; Merck & CO. (2001). [RM-403001]
  • ▲1.  O’Neil, M.J., Smith, A. et Heckelman, P.E., The Merck index : an encyclopedia of chemicals, drugs, and biologicals. 13th ed. Cambridge, MA : Cambridge Soft; Merck & CO. (2001). [RM-403001]
  • ▲2.  IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, Some naturally occuring and synthetic food components, furocoumarins and ultraviolet radiation. IARC monographs on the evaluation of carcinogenic risks to humans, Vol. 40. Lyon : International Agency for Research on Cancer. (1986).   https://monographs.iarc.fr/wp-content/uploads/2018/06/mono40.pdf
    http://www.iarc.fr
  • ▲2.  IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, Some naturally occuring and synthetic food components, furocoumarins and ultraviolet radiation. IARC monographs on the evaluation of carcinogenic risks to humans, Vol. 40. Lyon : International Agency for Research on Cancer. (1986).   https://monographs.iarc.fr/wp-content/uploads/2018/06/mono40.pdf
    http://www.iarc.fr
  • ▲2.  IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, Some naturally occuring and synthetic food components, furocoumarins and ultraviolet radiation. IARC monographs on the evaluation of carcinogenic risks to humans, Vol. 40. Lyon : International Agency for Research on Cancer. (1986).   https://monographs.iarc.fr/wp-content/uploads/2018/06/mono40.pdf
    http://www.iarc.fr
  • ▲3.  Report on Carcinogens, 11th edition. Research Triangle Park, NC : U.S. Department of Health and Human Services, Public Health Service, National Toxicology Program. (2005).   http://ntp.niehs.nih.gov/index.cfm?objectid=32BA9724-F1F6-975E-7FCE50709CB4C932
  • ▲3.  Report on Carcinogens, 11th edition. Research Triangle Park, NC : U.S. Department of Health and Human Services, Public Health Service, National Toxicology Program. (2005).   http://ntp.niehs.nih.gov/index.cfm?objectid=32BA9724-F1F6-975E-7FCE50709CB4C932
  • ▲4.  Schumann, R, «In vitro absorption of butylated hydroxyanisole through human skin .» J. Soc. Cosmet. Chem. Vol. 42, p. 335-340. (1991).
  • ▲5.  Kroes, R. et Westerm, P.W., «Forestomach carcinogens: possible mechanisms of action.» Food and Chemical Toxicology. Vol. 24, no. 10/11, p. 1083-1089. (1986).
  • ▲6.  Roed-Petersen, J. et Hjorth, N., «Contact dermatitis from antioxidants - Hidden sensitizers in topical medications and foods.» British Journal of Dermatology. Vol. 94, no. 3, p. 233-241. (1976). [AP-010658]
  • ▲7.  Goodman, D.L. et al., «Chronic urticaria exacerbated by the antioxidant food preservatives, butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT).» Journal of Allergy and Clinical Immunology. Vol. 86, no. 4 (pt 1), p. 570-575. (1990).
  • ▲8.  Tosti, A., Bardazzi, F. et Russo, R., «Contact dermatitis from butylated hydroxyanisole.» Contact Dermatitis. Vol. 17, no. 4, p. 257-258. (1987).
  • ▲9.  Gola, M. et al., «Allergic contact dermatitis in a pastry cook.» Contact Dermatitis. Vol. 21, p. 57. (1989). [AP-000164]
  • ▲10.  Rich, P. et al., «Allergic contact dermatitis to two antioxidants in latex gloves : 4,4'-thiobis(6-tert-butyl-meta-cresol) (Lowinox 44S36) and butylhydroxyanisole. Allergen atlernatives for glove-allergic patients.» Journal of the American Academy of Dermatology. Vol. 24, no. 1, p. 37-43. (1991).
  • ▲11.  Orton, D.I. et Shaw, S., «Allergic contact dermatitis from pharmaceutical grade BHA in Timodine, with no patch test reaction to analytical grade BHA.» Contact Dermatitis. Vol. 44, no. 3, p. 191-192. (2001).
  • ▲12.  White, I.R., Lovell, C.R. et Cronin, E., «Antioxidants in cosmetics.» Contact Dermatitis. Vol. 11, no. 5, p. 265-267. (1984).
  • ▲13.  IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, Overall evaluations of carcinogenicity : an updating of IARC monographs volumes 1-42. IARC monographs on the evaluation of carcinogenic risks to humans, Supplement 7. Lyon : International Agency for Research on Cancer. (1987).   https://monographs.iarc.fr/wp-content/uploads/2018/06/Suppl7.pdf
    http://monographs.iarc.fr/
  • ▲13.  IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, Overall evaluations of carcinogenicity : an updating of IARC monographs volumes 1-42. IARC monographs on the evaluation of carcinogenic risks to humans, Supplement 7. Lyon : International Agency for Research on Cancer. (1987).   https://monographs.iarc.fr/wp-content/uploads/2018/06/Suppl7.pdf
    http://monographs.iarc.fr/
  • ▲14.  Report on Carcinogens, 15th edition. Research Triangle Park, NC : U.S. Department of Health and Human Services, Public Health Service, National Toxicology Program. (2021).   https://ntp.niehs.nih.gov/pubhealth/roc/index-1.html
  • ▲14.  Report on Carcinogens, 15th edition. Research Triangle Park, NC : U.S. Department of Health and Human Services, Public Health Service, National Toxicology Program. (2021).   https://ntp.niehs.nih.gov/pubhealth/roc/index-1.html
  • ▲15.  IFA-Gestis, Information system on hazardous substances of the German Social Accident Insurance. Sankt Augustin, Germany : Institut für Arbeitsschutz der Deutschen Gesetzlichen Unfallversicherung (IFA).   https://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp

Autres sources d'information

  • Lewis, R.J., Sax's dangerous properties of industrial materials. Vol. 1, 8ème éd. New York : Van Nostrand Reinhold. (1992).
  • Lenga, R.E., The Sigma-Aldrich library of chemical safety data. 2nd ed. Milwaukee : Sigma-Aldrich. (1988).
  • Patty, F.A., Patty's industrial hygiene and toxicology. Vol. 2, 3rd ed. New York : John Wiley & Son. (1978).
  • Budavari, S. et O'Neil, M., The Merck index : an encyclopedia of chemicals, drugs, and biologicals. 11th ed. Rahway ( N.J.) : Merck. (1989). [RM-403001]
  • Fisherman, E.W. et Cohen, G. , «Chemical intolerance to butylated-hydroxyanisole (BHA) and butylated-hydroxytoluene (BHT) and vascular response as an indicator and monitor of drug intolerance.» Annals of Allergy. Vol. 31, p. 126-133. (1973). [AP-021563]
  • Cronin, E., Contact dermatitis. New York : Churchill Livingstone. (1980). [RM-015008]
  • ADVANCES IN FOOD RESEARCH, VOL. 3, 1951, P. 197-208 [AP-028048]
  • Fisher, A.A., Fisher's contact dermatitis. 3ème. Philadelphia : Lea & Febiger. (1986).
  • Toxicology and Applied Pharmacology, VOL. 96, 1988, P.115-121
  • Foussereau, J., Les eczémas allergiques : cosmétologiques, thérapeutiques et vestimentaires. Paris : Masson. (1987). [MO-011268]
  • Lewis, R.J., Reproductively active chemicals : a reference guide. New York : Van Nostrand Reinhold. (1991). [RM-515081]
  • Lewis, R.J, Carcinogenically active chemicals : a reference guide. New York, N.Y. : Van Nostrand Reinhold. (1991). [RM-515077]
  • Shepard, T.H., Catalog of teratogenic agents. 6th ed. London : John Hopkins University Press. (1989).

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