Methyl tetrahydropthalic anhydride

Numéro CAS : 11070-44-3

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Identification

Description


Formule moléculaire brute : C9H10O3

Principaux synonymes

Noms français :

  • Anhydride de méthyl tétrahydrophtalique (MTHPA)
  • Anhydride méthyltétrahydrophtalique (MTHPA)
  • Anhydride tétrahydrométhylphtalique
  • Méthyltétrahydro-2-benzofurane-1,3-dione

Noms anglais :

  • 1,3-ISOBENZOFURANDIONE, TETRAHYDROMETHYL-
  • Methyl tetrahydrophthalic anhydride (MTHPA)
  • Methyl tetrahydropthalic anhydride
Commentaires 1

Il existe plusieurs isomères de l'anhydride tétrahydrométhylphtalique (MTHPA). Chaque isomère possède un numéro d'enregistrement unique (CAS). Le produit portant le CAS 11070-44-3 est l'un de ces isomères. 

Utilisation et sources d'émission 1

L'anhydride tétrahydrométhylphtalique (MTHPA) est utilisé dans la fabrication  :

  • d'agents de durcissement pour les résines époxy
  • de produits d'ajustement de viscosité
  • d'agents de transfert de chaleur.

Références

  • ▲1.  National Industrial Chemicals Notification & Assessment Scheme, Tetrahydrophthalic anhydrides and analogues: Human health tier II assessment. Inventory multi-tiered assessment and prioritisation (IMAP). Sydney, Australie : NICNAS. (2018).   https://www.nicnas.gov.au/chemical-information/imap-assessments/imap-group-assessment-report?assessment_id=10266#cas-A_11070-44-3
  • ▲1.  National Industrial Chemicals Notification & Assessment Scheme, Tetrahydrophthalic anhydrides and analogues: Human health tier II assessment. Inventory multi-tiered assessment and prioritisation (IMAP). Sydney, Australie : NICNAS. (2018).   https://www.nicnas.gov.au/chemical-information/imap-assessments/imap-group-assessment-report?assessment_id=10266#cas-A_11070-44-3
  • ▲2.  OECD, «SIDS Initial Assessment Report for SIAM 15 - Tetrahydromethyl-1,3-isobenzofuranedione ( CAS : 11070-44-3).» In: OECD Screening Information Data Set (SIDS) . Paris : UNEP Publications. (2002).   http://www.inchem.org/documents/sids/sids/11070443.pdf
  • ▲2.  OECD, «SIDS Initial Assessment Report for SIAM 15 - Tetrahydromethyl-1,3-isobenzofuranedione ( CAS : 11070-44-3).» In: OECD Screening Information Data Set (SIDS) . Paris : UNEP Publications. (2002).   http://www.inchem.org/documents/sids/sids/11070443.pdf
  • ▲3.  IFA-Gestis, Information system on hazardous substances of the German Social Accident Insurance. Sankt Augustin, Germany : Institut für Arbeitsschutz der Deutschen Gesetzlichen Unfallversicherung (IFA).   https://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
  • ▲4.  Welinder, H. et al., «Decline in serum antibodies to methyltetrahydrophthalic anhydride after cessation of exposure. Implications for use as a biomarker.» Biomarkers. Vol. 3, no. 2, p. 141-148. (1998).
  • ▲5.  Yokota, K. et al., «The significance of specific IgG4 antibodies to methyltetrahydrophthalic anhydride in occupationally exposed subjects.» Clinical and Experimental Allergy. Vol. 28, no. 6, p. 694-701. (1998).
  • ▲6.  Yokota, K. et al., «Study on allergic rhinitis in workers exposed to methyltetrahydrophthalic anhydride.» Environmental Health and Preventive Medicine. Vol. 1, no. 3, p. 133-135. (1996).
  • ▲7.  Yokota, K. et al., «Risk factors for sensitization to methyltetrahydrophthalic anhydride.» Occupational and Environmental Medicine. Vol. 54, no. 9, p. 667-670. (1997).
  • ▲8.  Tarvainen, K. et al., «Immunologic contact urticaria due to airborne methylhexahydrophthalic and methyltetrahydrophthalic anhydrides.» Contact Dermatitis. Vol. 32, p. 204-209. (1995). [AP-022685]
  • ▲9.  Drexler, H. et al., «Detection and clinical relevance of a type I allergy with occupational exposure to hexahyrophthalic anhydride and methyltetrahydrophthalic anhydride.» International Archives of Occupational and Environmental Health. Vol. 65, p. 279-283. (1994).
  • ▲10.  Yokota, K. et al., «Exposure-response relationship in rhinitis and conjunctivitis caused by methyltetrahydrophthalic anhydride.» International Archives of Occupational and Environmental Health. Vol. 72, p. 14-18. (1999).
  • ▲11.  Nielsen, J., Welinder, H. et Skerfving, S., «Allergic airway disease caused by methyl tetrahydrophthalic anhydride in epoxy resin.» Scandinavian Journal of Work, Environment & Health. Vol. 15, p. 154-155. (1989).
  • ▲12.  Yokota, K. et al., «Specific antibodies against methyltetrahydrophthalic anhydride and risk factors for sensitization in occupationally exposed subjects.» Scandinavian Journal of Work, Environment & Health. Vol. 23, p. 214-220. (1997).
  • ▲13.  Nielsen, J. et al., «Allergy to methyltetrahydrophthalic anhydride in epoxy resin workers.» British Journal of Industrial Medicine. Vol. 49, p. 769-775. (1992).
  • ▲14.  Kalimo, K. et al., «IgE-mediated allergy to methyltetrahydrophthalic anhydride among workers producing electrical components.» Contact Dermatitis. Vol. 23, p. 280. (1990).
  • ▲15.  American Conference of Governmental Industrial Hygienists, «Methyltetrahydrophthalic anhydride isomers.» In: Documentation of the threshold limit values and biological exposure indices / Documentation of TLV's and BEI's. Cincinnati, Ohio : ACGIH. (2019). Publication #0100Doc.   http://www.acgih.org
  • ▲16.  Welinder, H. et Nielsen, J., «Immunologic tests of specific antibodies to organic acid anhydrides.» Allergy. Vol. 46, p. 601-609. (1991). [AP-036844]
  • ▲17.  ECHA (European Chemicals Agency) , Information on chemicals (REACH)/ECHA chemicals database. Helsinki, Finland.   http://echa.europa.eu/information-on-chemicals/registered-substances
    https://chem.echa.europa.eu/

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