Chlorhydrate d'hydralazine

Numéro CAS : 304-20-1

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L'information disponible sur cette substance est partielle. Pour de plus amples renseignements, veuillez communiquer avec le Répertoire toxicologique.

Identification

Description


Formule moléculaire brute : C8H9CLN4

Principaux synonymes

Noms français :

  • Chlorhydrate d'hydralazine

Noms anglais :

  • 1(2H)-PHTHALAZINONE, HYDRAZONE, MONOHYDROCHLORIDE
  • Hydralazine hydrochloride
  • HYDRALAZINE MONOHYDROCHLORIDE
  • PHTHALAZINONE, HYDRAZONE, MONOHYDROCHLORIDE

Références

  • ▲1.  Kligman, A.M., «The identification of contact allergens by human assay. III. The maximization test : a procedure for screening and rating contact sensitizers.» Journal of Investigative Dermatology. Vol. 47, no. 5, p. 393-409. (1966). [AP-022756]
  • ▲2.  Mayer, R.L., Eisman, P.C. et Jaconia, D., «Experimental sensitization of guinea-pigs to 1-hydrazinophthalazine; with discussion of the use of guinea-pigs for the forecast of clinical sensitizations.» Journal of Investigative Dermatology. Vol. 24, p. 281-291. (1955).
  • ▲3.  Katsutani, N. et Shionoya, H., «Drug-specific immune responses induced by immunization with drugs in guinea pigs and mice.» Journal of Toxicological Sciences. Vol. 17, no. 4, p. 169-183. (1992).
  • ▲4.  Kligman, A.M. et Magnusson, B., «The identification of contact allergens by animal assay : the guinea pig maximization test.» Journal of investigative dermatology. Vol. 52, no. 3, p. 268-276. (1969).   http://www.nature.com/jid/journal/v52/n3/pdf/jid196942a.pdf
  • ▲5.  van Ketel, W.G., «Contact dermatitis from a hydrazine-derivate in a stain remover. Cross sensitization to apresoline and isoniazid.» Acta Dermato-Venereologica. Vol. 44, p. 49-53. (1964). [AP-033591]
  • ▲6.  IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, Overall evaluations of carcinogenicity : an updating of IARC monographs volumes 1-42. IARC monographs on the evaluation of carcinogenic risks to humans, Supplement 7. Lyon : International Agency for Research on Cancer. (1987).   https://monographs.iarc.fr/wp-content/uploads/2018/06/Suppl7.pdf
    http://monographs.iarc.fr/
  • ▲7.  IARC Working Group on the Evaluation of Carcinogenic Risks of Chemical to Humans, Some pharmaceutical drugs. IARC monographs on the evaluation of the carcinogenic risk, Vol. 24. Lyon : International Agency for Research on Cancer. (1980).   https://monographs.iarc.fr/wp-content/uploads/2018/06/mono24.pdf
    http://www.iarc.fr

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