WHMIS (Octamethylcyclotetrasiloxane)

Workplace Hazardous Materials Information System

WHMIS 2015 classification - Note to reader

• Flammable liquids - Category 31 2
• Flash point = 51 °C closed cup (non reported method)

• Reproductive toxicity - Category 23 4 5 6 7
• Toxic to the reproductive function

Warning

Flammable liquid and vapour (H226)
Suspected of damaging fertility or the unborn child (H361)

Ingredient disclosure

References

• ▲1.  ECHA (European Chemicals Agency) , Information on chemicals (REACH)/ECHA chemicals database. Helsinki, Finland.   http://echa.europa.eu/information-on-chemicals/registered-substances
  https://chem.echa.europa.eu/
• ▲2.  IFA-Gestis, Information system on hazardous substances of the German Social Accident Insurance. Sankt Augustin, Germany : Institut für Arbeitsschutz der Deutschen Gesetzlichen Unfallversicherung (IFA).   https://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
• ▲3.  France. Institut national de recherche et de sécurité, Fiche toxicologique no 271 : Octaméthylcyclotétrasiloxane. Cahiers de notes documentaires. Paris : INRS. (2008). [RE-005509]   http://www.inrs.fr/publications/bdd/fichetox.html
  http://www.inrs.fr/publications/bdd/fichetox/fiche.html?refINRS=FICHETOX_271
• ▲4.  France. Institut national de recherche et de sécurité, Fiche Demeter : Octaméthylcyclotétrasiloxane. Paris : INRS. (2010).   http://www.inrs.fr/publications/bdd/demeter/demeter-CAS.html
• ▲5.  Meeks R.G. et al., «An inhalation reproductive toxicity study of octamethylcyclotetrasiloxane (D4) in female rats using multiple and single day exposure regimens..» Reproductive Toxicology. Vol. 23, no. 2, p. 192-201. (2007).   https://www.sciencedirect.com/science/article/pii/S0890623806003017?via%3Dihub
• ▲6.  Siddiqui W.H. et al., «A two-generation reproductive toxicity study of decamethylcyclopentasiloxane (D5) in rats exposed by whole-body vapor inhalation.» Reproductive Toxicology. Vol. 23, no. 2, p. 216-225. (2007).   https://www.sciencedirect.com/science/article/pii/S0890623806002747?via%3Dihub
• ▲7.  Quinn A.L. et al., «Effects of octamethylcyclotetrasiloxane (D4) on the luteinizing hormone (LH) surge and levels of various reproductive hormones in female Sprague-Dawley rats..» Reproductive Toxicology. Vol. 23, no. 4, p. 532-540. (2007).   https://www.sciencedirect.com/science/article/pii/S0890623807000342?via%3Dihub

The [number] refers to the Information SST database of the CNESST Documentation Center.