WHMIS (Toluene diisocyantate)

Workplace Hazardous Materials Information System

WHMIS 2015 classification - Note to reader

• Acute toxicity - inhalation - Category 21 2

• Skin corrosion/irritation - Category 21 2 3

• Serious eye damage/eye irritation - Category 2A1 2 4 5

• Respiratory sensitization - Category 11 2

• Skin sensitization - Category 1A1 2 4

• Carcinogenicity - Category 21

• Specific target organ toxicity - single exposure (respiratory tract irritation) - Category 3 - Respiratory tract irritation1

Danger

Fatal if inhaled (H330)
Causes skin irritation (H315)
Causes serious eye irritation (H319)
May cause allergy or asthma symptoms or breathing difficulties if inhaled (H334)
May cause allergic skin reaction (H317)
Suspected of causing cancer (H351)
May cause respiratory irritation (H335)

Ingredient disclosure

References

• ▲1.  Centre canadien d'hygiène et de sécurité au travail, CHEMINFO, Hamilton, Ont. : Canadian Centre for Occupational Health and Safety   http://ccinfoweb.ccohs.ca/cheminfo/search.html
• ▲2.  France. Institut national de recherche et de sécurité, Fiche toxicologique no 46 : Diisocyanate de toluylène. Cahiers de notes documentaires. Paris : INRS. (2006). [RE-005509]   http://www.inrs.fr/publications/bdd/fichetox.html
  http://www.inrs.fr/publications/bdd/fichetox/fiche.html?refINRS=FICHETOX_46
• ▲3.  Duprat, P., Gradiski, D. et Marignac, B., «Pouvoir irritant et allergisant de deux isocyanates, Toluène diisocyanate (TDI), Diphénylméthane diisocyanate (MDI).» European Journal of Toxicology. Vol. 9, no. 1, p. 41-53. (1976). [AP-023245]
• ▲4.  ECHA (European Chemicals Agency) , Information on chemicals (REACH)/ECHA chemicals database. Helsinki, Finland.   http://echa.europa.eu/information-on-chemicals/registered-substances
  https://chem.echa.europa.eu/
• ▲5.  Grant, W.M. et Schuman, J.S., Toxicology of the eye : effects on the eyes and visual systems from chemicals, drugs, metals and minerals, plants, toxins and venoms; also, systemic side effects from eye medications. Vol. 1, 4th ed. Springfield (ILL.) : Charles C. Thomas. (1993). [RM-515030]

The [number] refers to the Information SST database of the CNESST Documentation Center.