WHMIS (Cadmium)

Workplace Hazardous Materials Information System

WHMIS 2015 classification - Note to reader

• Combustible dusts - See comments below1

• Acute toxicity - inhalation - Category 11 2 3 4 5 6

• Germ cell mutagenicity - Category 21 7

• Carcinogenicity - Category 1A1 7 8 9 10 11

• Reproductive toxicity - Category 21 4 12 13 14 15 16
• Toxic to the reproductive function
• Toxic to the development

• Specific target organ toxicity - repeated exposure - Category 11 5 10 11

Danger

Fatal if inhaled (H330)
Suspected of causing genetic defects (H341)
May cause cancer (H350)
Suspected of damaging fertility or the unborn child (H361)
Causes damage to organs through prolonged or repeated exposure (H372)

Ingredient disclosure

Comments:

The toxicity of cadmium compounds is related to the presence of Cd2+ ion. Thus, the classification is based on the toxicity of this ion and takes account of the data available for all cadmium compounds"

References

• ▲1.  France. Institut national de recherche et de sécurité, Fiche toxicologique no 60 : Cadmium et composés minéraux. Cahiers de notes documentaires. Paris : INRS. (2022). [RE-005509]   http://www.inrs.fr/publications/bdd/fichetox.html
  http://www.inrs.fr/publications/bdd/fichetox/fiche.html?refINRS=FICHETOX_60
• ▲2.  National Institute for Occupational Safety and Health, RTECS (Registry of Toxic Effects of Chemical Substances). Hamilton (Ont) : Canadian Centre for Occupational Health and Safety.   http://ccinfoweb.ccohs.ca/rtecs/search.html
• ▲3.  Centre canadien d'hygiène et de sécurité au travail, CHEMINFO, Hamilton, Ont. : Canadian Centre for Occupational Health and Safety   http://ccinfoweb.ccohs.ca/cheminfo/search.html
• ▲4.  Bingham, E., Cohrssen, B. et Powell, C.H., Patty's toxicology. A Wiley-Interscience publication. New York (Toronto) : John Wiley. (2001-). [RM-214008]   http://www3.interscience.wiley.com (http://www3.interscience.wiley.com/cgi-bin/mrwhome/104554795/HOME)
• ▲5.  Bureau européen des substances chimiques, European Union Risk Assessment Report : Cadmium oxide and cadmiun metal . Vol. 72-74. Luxembourg : Office for Official Publications of the European Communities. (2007). EUR 22919/ 22767.   http://ecb.jrc.ec.europa.eu/DOCUMENTS/Existing-Chemicals/RISK_ASSESSMENT/REPORT/cdmetalreport303.pdf
• ▲6.  Yoshikawa, H et Homma, K, «Toxicity of inhaled metallic cadmium fumes in rats.» Japanese Journal of Industrial Health. Vol. 16, p. 212-215. (1974). [AP-018917]
• ▲7.  IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, A Review of Human Carcinogens: Arsenic, Metals, Fibres, and Dusts. IARC monographs on the evaluation of carcinogenic risks to humans, Vol. 100C. Lyon : International Agency for Research on Cancer. (2012).   http://monographs.iarc.fr/
  http://monographs.iarc.fr/ENG/Monographs/vol100C/mono100C.pdf
  
• ▲8.  Règlement sur la santé et la sécurité du travail [S-2.1, r. 13]. Québec : Éditeur officiel du Québec. [RJ-510071]   http://legisquebec.gouv.qc.ca/fr/ShowDoc/cr/S-2.1,%20r.%2013
• ▲9.  National Institute for Occupational Safety and Health, NIOSH pocket guide to chemical hazards. 3 ed. Cincinnati, Ohio : NIOSH. (2007). [RM-514001]   https://www.cdc.gov/niosh/npg/default.html
• ▲10.  American Conference of Governmental Industrial Hygienists, Documentation of the threshold limit values and biological exposure indices / Documentation of TLV's and BEI's. 7th ed. Cincinnati, Ohio : ACGIH. (2001-). Publication #0100Doc. [RM-514008]   http://www.acgih.org
• ▲11.  IPCS (International Programme on Chemical Safety), Cadmium. ICSC#0020. IPCS, CEC. (2005).   http://www.inchem.org/documents/icsc/icsc/eics0020.htm
• ▲12.  Schardein, J.L., Chemically induced birth defects. 3ème rév. & expanded. New York : Dekker. (2000). [MO-122294]
• ▲13.  Bureau européen des substances chimiques, European Union Draft Risk Assessment Report : Cadmium oxide and cadmium metal. 3rd Priority List. Luxembourg : Office for Official Publications of the European Communities. (2003).   http://ecb.jrc.ec.europa.eu/esis/
  http://ecb.jrc.it//DOCUMENTS/Existing-Chemicals/RISK_ASSESSMENT/DRAFT/R303_0307_env_hh.pdf
• ▲14.  Baranski, B., «Behavioral alterations in offspring of female rats repeatedly exposed to cadmium oxide by inhalation.» Toxicology Letters. Vol. 22, p. 53-61. (1984). [AP-021176]
• ▲15.  Schroeder, H.A. et Mitchener, M., «Toxic effects of trace elements on the reproduction of mice and rats.» Archives of environmental health. Vol. 23, no. 2, p. 102-106. (Aug. 1971). [AP-000933]
• ▲16.  Baranski, B, «Effect of exposure of pregnant rats to cadmium on prenatal and postnatal development of the young.» Journal of Hygiene, epidemiology, microbiology and immunology. Vol. 29, no. 3, p. 253-262. (1985). [AP-021174]

The [number] refers to the Information SST database of the CNESST Documentation Center.