CAS Number : 127-65-1

WHMIS (Chloramine-T)

Workplace Hazardous Materials Information System

WHMIS 2015 classification - Note to reader
Update: 2016-06-28

  • Combustible dusts - See comments below1
  • Acute toxicity - oral - Category 42 3
  • Skin corrosion/irritation - Category 22 3 4
  • Serious eye damage/eye irritation - Category 23 5
  • Respiratory sensitization - Category 13 6 7 8 9 10 11 12

  • WHMIS 2015 pictogram : Exclamation mark

  • WHMIS 2015 pictogram : Health hazard

Warning

Harmful if swallowed (H302)
Causes skin irritation (H315)
Causes serious eye irritation (H319)
May cause allergy or asthma symptoms or breathing difficulties if inhaled (H334)
May cause allergic skin reaction (H317)

Ingredient disclosure

Comments19 20 :

A thermally unstable substance liable to undergo a strongly exothermic decomposition. Laboratory testing performed on the substance as packaged is nescessary to determine the category (Type A to G) of this hazard class.

This product could belong to the hazard class "Combustible dust", based on various factors related to the combustibility and explosiveness of its dust, including composition, shape and size of the particles.

References

  • ▲1.  BGIA-Gestis, Information system on hazardous substances of the Berufsgenossenschaften. Sankt Augustin, Germany : Berufsgenossenschaftliches Institut.   http://gestis-database.dguv.de
  • ▲2.  EMEA (The European Agency for the Evaluation of Medicinal Products), Committee for Veterinary Medicinal Products: Tosylchloramide Sodium - Summary Report. London. (1999).   http://www.ema.europa.eu/docs/en_GB/document_library/Maximum_Residue_Limits_-_Report/2009/11/WC500015637.pdf. www.eudra.org/emea.html
  • ▲3.  Masten, S. et Haneke, K. E., Chloramine-T [127-65-1] and Metabolite p-Toluenesulfonamide [70-55-3] Review of Toxicological Literature. Research Triangle Park : National Institute of Environmental Health Sciences. (2002).   http://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/chloraminet_508.pdf
  • ▲4.  ECHA (European Chemicals Agency) , Information on Chemicals (REACH). Helsinki, Finland.  

    http://echa.europa.eu/information-on-chemicals/registered-substances
    ECHA CHEM (europa.eu)


  • ▲5.  Grant, W.M. et Schuman, J.S., Toxicology of the eye : effects on the eyes and visual systems from chemicals, drugs, metals and minerals, plants, toxins and venoms; also, systemic side effects from eye medications. Vol. 1, 4th ed. Springfield (ILL.) : Charles C. Thomas. (1993). [RM-515030]
  • ▲6.  Wass, U., Belin, L. et Eriksson, N.E., «Immunological specificity fo chloramine-T-induced IgE antibodies in serum from a sensitized worker.» Clinical and Experimental Allergy. Vol. 19, no. 4, p. 463-471. (1989).
  • ▲7.  Blasco, A. et al., «Bronchial asthma due to sensitization to chloramine T.» J. Invest. Allergol. Clin. Immunol.. Vol. 2, no. 3, p. 167-170. (1992).
  • ▲8.  Jouannique, V. et al., «Asthme professionnel à la chloramine T. À propos de deux observations.» Archives des maladies professionnelles, de médecine du travail et de sécurité sociale. Vol. 53, p. 654-657. (1992).
  • ▲9.  Rosenberg, N., «Asthme professionnel dû à la manipulation de chloramine T.» Documents pour le médecin du travail. Vol. 47, no. 22, p. 243-245. (1991).
  • ▲10.  Bourne, M.S., Flindt, M.L.H. et Walker, J. M., «Asthma due to industrial use of chloramine.» British Medical Journal. Vol. 2, p. 10-12. (1979). [AP-028001]
  • ▲11.  Asthmagen? : critical assessments of the evidence for agents implicated in occupational asthma. Health and Safety Executive. Sudbury, Suffolk, G.B. : HSE Books. (2001). [MO-020018]   http://www.hse.gov.uk/asthma/asthmagen.pdf
  • ▲12.  Sartorelli, P. et al., «Asthma induced by chloramine T in nurses : case report.» Medicina Del Lavoro. Vol. 101, no. 2, p. 134-138. (2010).
  • ▲13.  Basketter, D.A. et Scholes, E.W., «Comparison of the local lymph node assay with the guinea-pig maximization test for the detection of a range of contact allergens.» Food and Chemical Toxicology. Vol. 30, no. 1, p. 65-69. (1992).
  • ▲14.  Kimber, I. et al., «The local lymph node assay : developments and applications.» Toxicology. Vol. 93, no. 1, p. 13-31. (1994). [AP-063496]
  • ▲15.  de Groot, A.C. et al., «Contact allergy to preservatives - II.» Contact Dermatitis. Vol. 15, p. 218-222. (1986). [AP-023677]
  • ▲16.  Dooms-Goossens, A. et al., «Allergic contact urticaria due to chloramine.» Contact Dermatitis. Vol. 9, p. 319-320. (1983). [AP-028032]
  • ▲17.  Burnett, C. et al., «Evaluation of the toxicity and carcinogenicity of hair dyes.» Journal of Toxicology and Environmental Health. Vol. 6, p. 247-257. (1980).
  • ▲18.  document effacé.
  • ▲19.  Lewis, RJ., Sax's dangerous properties of industrial materials : H-Z. Vol. 3, 9ème éd. New York : Van Nostrand Reinhold. (1996).
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The [number] refers to the Information SST database of the CNESST Documentation Center.