WHMIS (Butyl glycidyl ether)

Workplace Hazardous Materials Information System

WHMIS 2015 classification - Note to reader

• Flammable liquids - Category 31
• Flash point = 56 °C Setaflash closed cup

• Acute toxicity - oral - Category 42 3 4 5

• Acute toxicity - inhalation - Category 36

• Skin sensitization - Category 17 8 9 10 11 12 13 14 15 16 17 18

• Germ cell mutagenicity - Category 27 19

• Carcinogenicity - Category 220

• Reproductive toxicity - Category 27 19

Danger

Flammable liquid and vapour (H226)
Harmful if swallowed (H302)
Toxic if inhaled (H331)
May cause allergic skin reaction (H317)
Suspected of causing genetic defects (H341)
Suspected of causing cancer (H351)
Suspected of damaging fertility or the unborn child (H361)

Ingredient disclosure

References

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• ▲2.  National Institute for Occupational Safety and Health, RTECS (Registry of Toxic Effects of Chemical Substances). Hamilton (Ont) : Canadian Centre for Occupational Health and Safety.   http://ccinfoweb.ccohs.ca/rtecs/search.html
• ▲3.  Centre canadien d'hygiène et de sécurité au travail, CHEMINFO, Hamilton, Ont. : Canadian Centre for Occupational Health and Safety   http://ccinfoweb.ccohs.ca/cheminfo/search.html
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• ▲5.  American Conference of Governmental Industrial Hygienists, «n-Butyl glycidyl ether (CAS 2426-08-6).» In: Documentation of the threshold limit values and biological exposure indices / Documentation of TLV's and BEI's. Cincinnati, Ohio : ACGIH. (2014). Publication #0100Doc.   http://www.acgih.org
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• ▲7.  American Conference of Governmental Industrial Hygienists, Documentation of the threshold limit values and biological exposure indices / Documentation of TLV's and BEI's. 7th ed. Cincinnati, Ohio : ACGIH. (2001-). Publication #0100Doc. [RM-514008]   http://www.acgih.org
• ▲8.  Kligman, A.M., «The identification of contact allergens by human assay. III. The maximization test : a procedure for screening and rating contact sensitizers.» Journal of Investigative Dermatology. Vol. 47, no. 5, p. 393-409. (1966). [AP-022756]
• ▲9.  Fregert, S. et Rorsman, H., «Allergens in epoxy resins.» Acta Allergologica. Vol. 19, p. 296-299. (1964). [AP-024597]
• ▲10.  Jolanki, R. et al., «Occupational dermatoses from epoxy resin compounds.» Contact Dermatitis. Vol. 23, no. 3, p. 172-183. (1990). [AP-031278]
• ▲11.  Tarvainen, K., «Analysis of patients with allergic patch test reactions to a plastics and glues series.» Contact Dermatitis. Vol. 32, p. 346-351. (1995). [AP-050850]
• ▲12.  Basketter, D.A., Scholes, E.W. et Kimber, I., «The performance of the local lymph node assay with chemicals identified as contact allergens in the human maximization test.» Food and Chemical Toxicology. Vol. 32, no. 6, p. 543-547. (1994).
• ▲13.  CBI / Glycidol and its derivatives. (1982). Microfiche : OTS206089
• ▲14.  Ciba-Geigy, Skin sensitizing (contact allergenic) effect in guinea pigs of TK-10408 (glycidyl n-butyl ether). (1977). Microfiche : OTS0515486, 86870001325
• ▲15.  Murine local lymph node assay: a test method for assessing the allergenic contact dermatitis potential of chemical compounds. (1999). Microfiche : PB2001-104492, NIH-PUB-99-4494
• ▲16.  Basketter, D.A. et al., «The local lymph node assay : a viable alternative to currently accepted skin sensitization tests.» Food and Chemical Toxicology. Vol. 34, p. 985-997. (1996). [AP-050952]
• ▲17.  Tosti, A. et al., «Occupational skin hazards from synthetic plastics.» Toxicology and Industrial Health. Vol. 9, no. 3, p. 493-502. (1993). [AP-042925]
• ▲18.  Bingham, E. et Cohrssen, B., Patty's toxicology. A Wiley-Interscience publication, 6ème éd. New York (NY) : John Wiley & Sons. (2012). [RM-214008]
• ▲19.  Whorton E.B. Jr. et al., «Dominant Lethal Effects of n-Butyl Glycidyl Ether in Mice.» Mutation Research. Vol. 124, p. 225-233. (1983). [AP-005583]
• ▲20.  IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, Some industrial chemical intermediates and solvents. IARC monographs on the evaluation of carcinogenic risks to humans, Vol. 125. Lyon : International Agency for Research on Cancer. (2020).   http://monographs.iarc.fr/
  Volume125.pdf

The [number] refers to the Information SST database of the CNESST Documentation Center.