The section entitled For a Maternity Experience program is not available in English for this substance. Consult the French version.

Programme pour une maternité sans danger (PMSD)

Propriétés physiques pertinentes 1

Mise à jour : 1990-09-15

Voies d'absorption

L'information relative à cette section n'est pas disponible actuellement.

Effets sur le développement 

Mise à jour : 1996-02-12

• Il a un effet embryotoxique et/ou foetotoxique chez l'animal.

Effets sur la reproduction 

Mise à jour : 1996-02-12

• Il peut causer des atteintes spermatiques chez l'animal.

Effets sur l'allaitement 

Mise à jour : 2019-05-06

• Il n'y a aucune donnée concernant l'excrétion ou la détection dans le lait.

Cancérogénicité 2 3 4 5 6 7 8 9

Mise à jour : 2012-03-06

Évaluation de la cancérogénicité par des organismes officiels

Le Centre international de recherche sur le cancer (CIRC, 2012) considère que l'oxyde d'éthylène est cancérogène pour l'homme (groupe 1).

L'ACGIH (2001) considère que l'oxyde d'éthylène est un cancérogène suspecté chez l'humain (groupe A2).

Le NTP (2011) considère l'oxyde d'éthylène comme étant un cancérogène reconnu chez l'humain (K).

Mutagénicité

Mise à jour : 1996-02-12

• Effet mutagène démontré chez l'animal ou soupçonné chez l'humain.

Références

• ▲1.  Kroschwitz, J.I., Kirk-Othmer encyclopedia of chemical technology : Embedding to Feeds and Feed Additives, Ruminant Feeds. Vol. 10, 5th ed. Hoboken, N.J. : John Wiley & Sons. (2004-). [RT-423004]
• ▲2.  Règlement sur la santé et la sécurité du travail [S-2.1, r. 13]. Québec : Éditeur officiel du Québec. [RJ-510071]   http://legisquebec.gouv.qc.ca/fr/ShowDoc/cr/S-2.1,%20r.%2013
• ▲3.  IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, Some industrial chemicals. IARC monographs on the evaluation of carcinogenic risks, Vol. 60. Lyon : International Agency for Research on Cancer. (1994).   https://monographs.iarc.fr/wp-content/uploads/2018/06/mono60.pdf
  http://www.iarc.fr
• ▲4.  IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 1,3-Butadiene, Ethylene Oxide and Vinyl Halides (Vinyl Fluoride, Vinyl Chloride and Vinyl Bromide). IARC monographs on the evaluation of carcinogenic risks to humans, Vol. 97. Lyon : International Agency for Research on Cancer. (2008).   http://monographs.iarc.fr/
• ▲5.  Baan, R. et al., «A review of human carcinogens - Part F : chemical agents and related occupations.» The Lancet Oncology. Vol. 10, no. 12, p. 1143-1144. (2009). [AP-069589]
• ▲6.  IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, A Review of Human Carcinogens: Chemical Agents and Related Occupations. IARC monographs on the evaluation of carcinogenic risks to humans, Vol. 100F. Lyon : International Agency for Research on Cancer. (2012).   http://monographs.iarc.fr/
  http://monographs.iarc.fr/ENG/Monographs/vol100F/index.php
• ▲7.  American Conference of Governmental Industrial Hygienists, TLVs® and BEIs® : threshold limit values for chemical substances and physical agents and biological exposure indices. Cincinnati (OH) : ACGIH. (2024). [NO-003164]   http://www.acgih.org
• ▲8.  Report on Carcinogens, 15th edition. Research Triangle Park, NC : U.S. Department of Health and Human Services, Public Health Service, National Toxicology Program. (2021).   https://ntp.niehs.nih.gov/pubhealth/roc/index-1.html
• ▲9.  American Conference of Governmental Industrial Hygienists, Documentation of the threshold limit values and biological exposure indices / Documentation of TLV's and BEI's. 7th ed. Cincinnati, Ohio : ACGIH. (2001-). Publication #0100Doc. [RM-514008]   http://www.acgih.org

Autres sources d'information

• American Conference of Governmental Industrial Hygienists, 2022 TLVs and BEIs with 7th edition documentation CD-ROM. Cincinnati, OH : ACGIH. (2022). Publication 0111CD. [CD-120061]   http://www.acgih.org
• National Fire Protection Association, Fire protection guide on hazardous materials. 9th ed. Quincy, Mass. : NFPA. (1986).   http://www.nfpa.org/
• Grant, W.M., Toxicology of the eye : effects on the eyes and visual systems from chemicals, drugs, metals and minerals, plants, toxins and venoms; also, systemic side effects from eye medications. 3rd. ed. Springfield (ILL) : Charles C. Thomas. (1986).
• Patty, F.A., Patty's industrial hygiene and toxicology. Vol. 2, 3rd ed. New York : John Wiley & Son. (1978).
• Air liquide. Division scientifique, Encyclopédie des gaz / Gas encyclopaedia, Amsterdam : Elsevier, 1976 [RS-403002]
• Braker, W. et Mossman, A.L., Matheson gas data book. Lundhurst, N.J. : Matheson. (1980). [RS-415003]
• Canutec. Guide de premières mesures d'urgence. Ottawa : Centre d'Édition du Gouvernement du Canada. (1986).
• Zenz, C. , «Reproductive risks in the workplace.» National Safety News. Vol. 130, no. 3, p. 38-46. (1984). [AP-004433]
• Fabro, S., Brown, N.A. et Scialli, A.R., «Ethylene oxide.» Reproductive Toxicology. Vol. 6, no. 2, p. 7-11. (1987). [AP-021947]
• ARCHIVES OF INDUSTRIAL HEALTH, VOL. 13, 1956, P. 237-244 [AP-130268]
• Environmental Mutagenesis, VOL. 8, 1986, P. 1-7
• Environmental Mutagenesis, VOL. 8, 1986, P. 867-872
• Mutation Research, VOL. 119, 1983, P. 377-379
• Mutation Research, VOL. 120, 1983, P. 37-44
• Mutation Research, VOL. 176, 1987, P. 269-274
• Scandinavian Journal of Work, Environment & Health, VOL. 9, 1983, P. 94-102
• Snellings, W.M. et al., «Teratology study in Fischer 344 rats exposed to ethylene oxide by inhalation.» Toxicology and Applied Pharmacology. Vol. 64, p. 476-481. (1982). [AP-130149]
• Toxicology and Applied Pharmacology, VOL. 56, 1980, P. 16-22 [AP-130167]
• Lynch, D.W. et al., «Sister-chromatid exchanges and chromosome-aberrations in lymphocytes from monkeys exposed to ethylene oxide and propylene oxide by inhalation.» Toxicology and Applied Pharmacology. Vol. 76, no. 1, p. 85-95. (1984). [AP-135470]
• Smyth, F.H., Seaton, J. et Fischer, L., «The single dose toxicity of some glycols and derivatives.» Journal of Industrial Hygiene and Toxicology. Vol. 23, no. 6, p. 259-268. (1941). [AP-021581]
• Material safety data sheets / Genium's Handbook of safety, health, and environmental data. Genium Publishing Corp. (1999-).   http://www.genium.com/hazmat/
• IARC Working Group on the Evaluation of Carcinogenic Risks of Chemical to Humans, Allyl compounds, aldehydes, epoxides and peroxides. IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans, Vol. 36. Lyon : International Agency for Research on Cancer. (1985).   https://monographs.iarc.fr/wp-content/uploads/2018/06/mono36.pdf
  http://www.iarc.fr
• National Institute for Occupational Safety and Health et États-Unis. Occupational Safety and Health Administration, Occupational health guidelines for chemical hazards. Vol. 1. Cincinnati : Centers for Disease Control. (1981-). DHSS-NIOSH 81-123. [RR-015002]   http://www.cdc.gov/niosh/docs/81-123/
• IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, Genetic and related effects : an updating of selected IARC monographs from volumes 1 to 42. IARC monographs on the evaluation of carcinogenic risks to humans, Supplement 6. Lyon : International Agency for Research on Cancer. (1987).   http://www.iarc.fr
• Shepard, T.H., Catalog of teratogenic agents. 6th ed. London : John Hopkins University Press. (1989).

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