WHMIS (Catechol)

Workplace Hazardous Materials Information System

WHMIS 2015 classification - Note to reader

• Acute toxicity - oral - Category 31 2 3 4

• Acute toxicity - dermal - Category 32 3 4

• Serious eye damage/eye irritation - Category 12 4 5

• Skin sensitization - Category 1B1 6 7 8 9 10 11 12

• Germ cell mutagenicity - Category 22 8 13

• Carcinogenicity - Category 21 4 14

• Specific target organ toxicity - single exposure - Category 11 2 8 15 16

• Specific target organ toxicity - single exposure (respiratory tract irritation) - Category 3 - Respiratory tract irritation1 2 8 15 16

Danger

Toxic if swallowed (H301)
Toxic in contact with skin (H311)
Causes serious eye damage (H318)
May cause allergic skin reaction (H317)
Suspected of causing genetic defects (H341)
Suspected of causing cancer (H351)
Causes damage to organs (H370)
May cause respiratory irritation (H335)

Ingredient disclosure

Comments: This product could belong to the hazard class "Combustible dust", based on various factors related to the combustibility and explosiveness of its dust, including composition, shape and size of the particles.

References

• ▲1.  American Conference of Governmental Industrial Hygienists, Documentation of the threshold limit values and biological exposure indices / Documentation of TLV's and BEI's. 7th ed. Cincinnati, Ohio : ACGIH. (2001-). Publication #0100Doc. [RM-514008]   http://www.acgih.org
• ▲2.  ECHA (European Chemicals Agency) , Information on Chemicals (REACH). Helsinki, Finland.  

  http://echa.europa.eu/information-on-chemicals/registered-substances
  ECHA CHEM (europa.eu)

  
  
• ▲3.  National Institute for Occupational Safety and Health, RTECS (Registry of Toxic Effects of Chemical Substances). Hamilton (Ont) : Canadian Centre for Occupational Health and Safety.   http://ccinfoweb.ccohs.ca/rtecs/search.html
• ▲4.  Centre canadien d'hygiène et de sécurité au travail, CHEMINFO, Hamilton, Ont. : Canadian Centre for Occupational Health and Safety   http://ccinfoweb.ccohs.ca/cheminfo/search.html
• ▲5.  Grant, W.M. et Schuman, J.S., Toxicology of the eye : effects on the eyes and visual systems from chemicals, drugs, metals and minerals, plants, toxins and venoms; also, systemic side effects from eye medications. Vol. 1, 4th ed. Springfield (ILL.) : Charles C. Thomas. (1993). [RM-515030]
• ▲6.  Morelli, R. et al., «Occupational contact dermatitis from pyrocatechol.» Contact Dermatitis. Vol. 21, p. 201-202. (1989).
• ▲7.  Itoh, M., «Sensitization potency of some phenolic compounds with special emphasis on the relationship between chemical structure and allergenicity.» Journal of Dermatology. Vol. 9, p. 223-233. (1982). [AP-016831]
• ▲8.  Bingham, E., Cohrssen, B. et Powell, C.H., Patty's toxicology. A Wiley-Interscience publication. New York (Toronto) : John Wiley. (2001-). [RM-214008]   http://www3.interscience.wiley.com (http://www3.interscience.wiley.com/cgi-bin/mrwhome/104554795/HOME)
• ▲9.  Hemmer, W. et al., «Group allergy to tri- and ortho-diphenols (catechols) in a patient sensitized by propyl gallate.» Contact Dermatitis. Vol. 35, no. 2, p. 110-112. (1996). [AP-029555]
• ▲10.  Leino, T. et al., «Occupational skin and respiratory diseases among hairdressers.» Scandinavian Journal of Work, Environment & Health. Vol. 24, no. 5, p. 398-406. (1998).
• ▲11.  Andersen, K.E. et Carlsen, L., «Pyrocatechol contact allergy from a permanent cream dye for eyelashes and eyebrows.» Contact Dermatitis. Vol. 18, no. 5, p. 306-307. (1988).
• ▲12.  Itoh M., «Sensitization Potency of Some Phenolic Compounds - With Special Emphasis on the Relationship Between Chemical Structure and Allergenicity.» The Journal of Dermatology. Vol. 9, p. 223-233. (1982). [AP-000439]
• ▲13.  National Library of Medicine, The Hazardous Substances Data Bank (HSDB). Hamilton (Ont.) : Canadian Centre for Occupational Health and Safety.   http://www.ccohs.ca/
• ▲14.  IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, Re-evaluation of some organic chemicals, hydrazine and hydrogen peroxide : part 1. IARC monographs on the evaluation of carcinogenic risks to humans, Vol. 71. Lyon : International Agency for Research on Cancer. (1999).   https://monographs.iarc.fr/wp-content/uploads/2018/06/mono71.pdf http://www.iarc.fr
• ▲15.  IARC Working Group on the Evaluation of Carcinogenic Risks of Chemical to Man, Some fumigants, the herbicides 2,4-D and 2,4,5-T, chlorinated dibenzodioxins and miscellaneous industrial chemicals. IARC monographs on the evaluation of carcinogenic risks of chemical to man, Vol. 15. Lyon : International Agency for Research on Cancer. (1977).   https://monographs.iarc.fr/wp-content/uploads/2018/06/mono15.pdf
  http://www.iarc.fr
• ▲16.  Hirosawa, I. et al., «Effects of catechol on human subjects.» International Archives of Occupational and Environmental Health. Vol. 37, p. 107-114. (1976). [AP-029073]

The [number] refers to the Information SST database of the CNESST Documentation Center.