WHMIS (Lithium carbonate)

Workplace Hazardous Materials Information System

WHMIS 2015 classification - Note to reader

• Acute toxicity - oral - Category 41 2 3 4

• Serious eye damage/eye irritation - Category 2B1

• Reproductive toxicity - Category 1A5 6 7 8 9 10
• Toxic to the development

• Specific target organ toxicity - repeated exposure - Category 11 3 6

Danger

Harmful if swallowed (H302)
Causes eye irritation (H320)
May damage fertility or the unborn child (risk of fetal cardiac malformations) (H360)
Causes damage to organs (central nervous system) through prolonged or repeated exposure (H372)

Ingredient disclosure

References

• ▲1.  ECHA (European Chemicals Agency) , Information on chemicals (REACH)/ECHA chemicals database. Helsinki, Finland.   http://echa.europa.eu/information-on-chemicals/registered-substances
  https://chem.echa.europa.eu/
• ▲2.  National Institute for Occupational Safety and Health, RTECS (Registry of Toxic Effects of Chemical Substances). Hamilton (Ont) : Canadian Centre for Occupational Health and Safety.   http://ccinfoweb.ccohs.ca/rtecs/search.html
• ▲3.  Centre canadien d'hygiène et de sécurité au travail, CHEMINFO, Hamilton, Ont. : Canadian Centre for Occupational Health and Safety   http://ccinfoweb.ccohs.ca/cheminfo/search.html
• ▲4.  Smyth, H.F., Carpenter, C.P. et Weil, C.S., «Range-Finding Toxicity Data : List VII.» American Industrial Hygiene Association Journal. Vol. 30, no. 5, p. 470-476. (1969). [AP-000464]
• ▲5.  Moore, J.A., «An assessment of lithium using the iehr evaluative process for assessing human developmental and reproductive toxicity of agents.» Reproductive Toxicology. Vol. 9, no. 2, p. 175-210. (1995). [AP-046801 ]
• ▲6.  NIOSH, Health hazard evaluation report, Lithium corporation of America. Bessemer City, North Carolina. (1981). HHE 80-036-922.
• ▲7.  Poels, E.M.P. et al., «Lithium during pregnancy and after delivery: a review.» International journal of bipolar disorders. Vol. 6, no. 26. (2018).   https://journalbipolardisorders.springeropen.com/articles/10.1186/s40345-018-0135-7
• ▲8.  Munk-Olsen, T. et al., «Maternal and infant outcomes associated with lithium use in pregnancy:.» Lancet psychiatry. Vol. 5, no. 8, p. 644-652. (2018).   https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077091/pdf/nihms-977891.pdf
• ▲9.  Patorno, E. et al., «Lithium Use in Pregnancy and the Risk of Cardiac Malformations.» The new england journal of medecine. Vol. 376, no. 23, p. 2245-2254. (2017).   https://www.nejm.org/doi/full/10.1056/NEJMoa1612222
• ▲10.  Diav-Citrin, O. et al., «Pregnancy Outcome Following in Utero Exposure to Lithium: A Prospective, Comparative, Observational Study .» The american journal of psychiatry. Vol. 171, no. 7, p. 785-794. (2014).   https://ajp.psychiatryonline.org/doi/full/10.1176/appi.ajp.2014.12111402?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed

The [number] refers to the Information SST database of the CNESST Documentation Center.