WHMIS (Acetonitrile)

Workplace Hazardous Materials Information System

WHMIS 2015 classification - Note to reader

• Flammable liquids - Category 21
• Flash point = 6 °C Setaflash closed cup and boiling point = 82 °C

• Acute toxicity - oral - Category 3

• Acute toxicity - dermal - Category 42 3 4

• Acute toxicity - inhalation - Category 32 5 6 7 8 9

• Serious eye damage/eye irritation - Category 2A10 11

Danger

Highly flammable liquid and vapour (H225)
Toxic if swallowed (H301)
Harmful in contact with skin (H312)
Toxic if inhaled (H331)
Causes serious eye irritation (H319)

Ingredient disclosure

References

• ▲1.  Lenga, R.E. et Votoupal, K.L., The Sigma-Aldrich library of regulatory and safety data. Vol. 1. Milwaukee : Sigma-Aldrich. (1993). [RM-515040]
• ▲2.  Pozzani, U.C. et al., «An Investigation of the Mammalian Toxicity of Acetonitrile.» Journal of Occupational Medicine. [AP-023886]
• ▲3.  Smyth, H.F. et Carpenter, C.P., «Further experience with the range finding test in the industrial toxicology laboratory.» Journal of Industrial Hygiene and Toxicology. Vol. 30, no. 1, p. 63-68. (1948). [AP-021359]
• ▲4.  Parent, R.A., «Acute Toxicity Data Submissions.» Internationnal Journal of Toxicology. Vol. 19, p. 331-373. (2000). [AP-060824]
• ▲5.  American Conference of Governmental Industrial Hygienists, Documentation of the threshold limit values and biological exposure indices / Documentation of TLV's and BEI's. 7th ed. Cincinnati, Ohio : ACGIH. (2001-). Publication #0100Doc. [RM-514008]   http://www.acgih.org
• ▲6.  National Institute for Occupational Safety and Health, RTECS (Registry of Toxic Effects of Chemical Substances). Hamilton (Ont) : Canadian Centre for Occupational Health and Safety.   http://ccinfoweb.ccohs.ca/rtecs/search.html
• ▲7.  France. Institut national de recherche et de sécurité, Fiche toxicologique no 104 : Acétonitrile. Cahiers de notes documentaires. Paris : INRS. (2017). [RE-005509]   http://www.inrs.fr/publications/bdd/fichetox.html
  http://www.inrs.fr/publications/bdd/fichetox/fiche.html?refINRS=FICHETOX_104
• ▲8.  Pozzani, U.C., Weil, C.S. et Carpenter, C.P., «The toxicological basis of threshold limit values : 5. the experimental inhalation of vapors mixtures by rats, with notes upon the relationship between single dose inhalation and single dose oral data.» American Industrial Hygiene Association Journal. Vol. 20, p. 364-369. (1959). [AP-023711]
• ▲9.  Willhite, C.C., «Inhalation toxicology of acute exposure to aliphatic nitriles.» Clinical Toxicology. Vol. 18, no. 8, p. 991-1003. (1981). [AP-060819]
• ▲10.  Centre canadien d'hygiène et de sécurité au travail, CHEMINFO, Hamilton, Ont. : Canadian Centre for Occupational Health and Safety   http://ccinfoweb.ccohs.ca/cheminfo/search.html
• ▲11.  Bureau européen des substances chimiques, European Union Risk Assessment Report : acetonitrile. 1st Priority List, Vol. 18. Luxembourg : Office for Official Publications of the European Communities. (2002). EUR 19839 EN.   http://echa.europa.eu/documents/10162/764c8da5-79e2-418d-bf1f-ab59592f8cc6

The [number] refers to the Information SST database of the CNESST Documentation Center.