WHMIS (Lead orthoarsenate)

Workplace Hazardous Materials Information System

WHMIS 2015 classification - Note to reader

• Acute toxicity - oral - Category 31 2 3 4

• Carcinogenicity - Category 1A5 6

• Reproductive toxicity - Category 1A1 4 7 8 9
• Toxic to the reproductive function
• Toxic to the development

• Specific target organ toxicity - repeated exposure - Category 11 4

Danger

Toxic if swallowed (H301)
May cause cancer (H350)
May damage fertility or the unborn child (H360)
Causes damage to organs through prolonged or repeated exposure (H372)

Ingredient disclosure

Comments: The toxicity of inorganic lead compounds is related to the presence of Pb2 + ion. Thus, the classification is based on the toxicity of this ion and takes account of the data available for all inorganic lead compounds..

References

• ▲1.  American Conference of Governmental Industrial Hygienists, Documentation of the threshold limit values and biological exposure indices / Documentation of TLV's and BEI's. 7th ed. Cincinnati, Ohio : ACGIH. (2001-). Publication #0100Doc. [RM-514008]   http://www.acgih.org
• ▲2.  National Institute for Occupational Safety and Health, RTECS (Registry of Toxic Effects of Chemical Substances). Hamilton (Ont) : Canadian Centre for Occupational Health and Safety.   http://ccinfoweb.ccohs.ca/rtecs/search.html
• ▲3.  National Library of Medicine, The Hazardous Substances Data Bank (HSDB). Hamilton (Ont.) : Canadian Centre for Occupational Health and Safety.   http://www.ccohs.ca/
• ▲4.  Krieger, R. et al., Handbook of pesticide toxicology : agents. Vol. 2, 2nd ed. New York : Academic Press. (2001). [RM-515024]
• ▲5.  Report on Carcinogens, 15th edition. Research Triangle Park, NC : U.S. Department of Health and Human Services, Public Health Service, National Toxicology Program. (2021).   https://ntp.niehs.nih.gov/pubhealth/roc/index-1.html
• ▲6.  IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, Inorganic and Organic Lead Compounds. IARC monographs on the evaluation of carinogenic risks to humans, Vol. 87. Lyon : International Agency for Research on Cancer. (2006).   http://monographs.iarc.fr/
• ▲7.  Joint WHO/FAO Expert Committee on Food Additives (JECFA ), «Lead ( Evaluation of health risk to infants and children).» In: WHO food additives series. Vol. 21. Genève : World Health Organization ; International Programme on Chemical Safety. (1987).   http://www.inchem.org/documents/jecfa/jecmono/v21je16.htm
• ▲8.  Ettinger, A.S. et al., «Maternal Blood, Plasma, and Breast Milk Lead: Lactational Transfer and Contribution to Infant Exposure.» Environmental Health Perspectives. Vol. 122, no. 1, p. 87-92. (2014).   http://ehp.niehs.nih.gov/wp-content/uploads/122/1/ehp.1307187.pdf http://ehp.niehs.nih.gov/1307187/
• ▲9.  Silbergeld, E.K., «Lead in Bone: Implications for Toxicology during Pregnancy and Lactation.» Environmental Health Perspectives. Vol. 91, p. 63-70. (1991).   http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1519355/pdf/envhper00387-0065.pdf

The [number] refers to the Information SST database of the CNESST Documentation Center.