WHMIS (Cobalt difluoride)

Workplace Hazardous Materials Information System

WHMIS 2015 classification - Note to reader

• Acute toxicity - oral - Category 31 2

• Respiratory sensitization - Category 13 4 5 6

• Skin sensitization - Category 17

• Carcinogenicity - Category 28

• Specific target organ toxicity - repeated exposure - Category 19

Danger

Toxic if swallowed (H301)
May cause allergy or asthma symptoms or breathing difficulties if inhaled (H334)
May cause allergic skin reaction (H317)
Suspected of causing cancer (H351)
Causes damage to organs through prolonged or repeated exposure (H372)

Ingredient disclosure

Comments: Due to the lack of data, classification regarding respiratory sensitization (H334), skin sensitization (H317) and specific organ toxicity - repeated exposure (H372) were established by analogy to Cobalt dichloride (inorganic Cobalt compounds).

References

• ▲1.  National Institute for Occupational Safety and Health, RTECS (Registry of Toxic Effects of Chemical Substances). Hamilton (Ont) : Canadian Centre for Occupational Health and Safety.   http://ccinfoweb.ccohs.ca/rtecs/search.html
• ▲2.  Speijers, G.J.A. et al., «Acute oral toxicity of inorganic cobalt compounds in rats.» Food and chemical toxicology. Vol. 20, no. 3, p. 311-314. (June 1982). [AP-000915]
• ▲3.  ECHA (European Chemicals Agency) , Information on chemicals (REACH)/ECHA chemicals database. Helsinki, Finland.   http://echa.europa.eu/information-on-chemicals/registered-substances
  https://chem.echa.europa.eu/
• ▲4.  Kusaka, Y. et al., «Respiratory diseases in hard metal workers : an occupational hygiene study in a factory.» British Journal of Industrial Medicine. Vol. 43, p. 474-485. (1986). [AP-013249]
• ▲5.  Shirakawa, T. et al., «The existence of specific antibodies to cobalt in hard metal asthma.» Clinical Allergy. Vol. 18, no. 5, p. 451-460. (1988). [AP-068447]
• ▲6.  Shirakawa, T. et al., «Occupational asthma from cobalt sensivity in workers exposed to hard metal dust.» Chest. Vol. 95, no. 1, p. 29-37. (1989). [AP-024259]
• ▲7.  France. Institut national de recherche et de sécurité, Fiche toxicologique no 128 : Cobalt et composés minéraux. Cahiers de notes documentaires. Paris : INRS. (2015). [RE-005509]   http://www.inrs.fr/publications/bdd/fichetox.html
  http://www.inrs.fr/publications/bdd/fichetox/fiche.html?refINRS=FICHETOX_128
• ▲8.  IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, Chlorinated drinking-water; chlorination by-products; so other halogenated compounds; cobalt and cobalt compounds. IARC monographs on the evaluation of carcinogenic risks to humans, Vol. 52. Lyon : International Agency for Research on Cancer. (1991).   https://monographs.iarc.fr/wp-content/uploads/2018/06/mono52.pdf
• ▲9.  Agency for Toxic Substances and Diseases Registry (ATSDR), , Toxicological profile for cobalt.. ATSDR. Washington D.C. : US Department of Health and Human Services. (2004).   http://www.atsdr.cdc.gov/toxprofiles/index.asp#C http://www.atsdr.cdc.gov/ToxProfiles/tp33.pdf

The [number] refers to the Information SST database of the CNESST Documentation Center.