WHMIS (Cobalt dibromide)

Workplace Hazardous Materials Information System

WHMIS 2015 classification - Note to reader

• Acute toxicity - oral - Category 41

• Respiratory sensitization - Category 12

• Skin sensitization - Category 13 4

• Carcinogenicity - Category 22 5 6

• Specific target organ toxicity - repeated exposure - Category 14 7 8 9 10

Danger

Harmful if swallowed (H302)
May cause allergy or asthma symptoms or breathing difficulties if inhaled (H334)
May cause allergic skin reaction (H317)
Suspected of causing cancer (H351)
Causes damage to organs through prolonged or repeated exposure (H372)

Ingredient disclosure

Comments: Due to the lack of data, classifications regarding respiratory sensitization (H334), skin sensitization (H317) and specific organ toxicity - repeated exposure (H372) were established by analogy to Cobalt dichloride.

References

• ▲1.  National Institute for Occupational Safety and Health, RTECS (Registry of Toxic Effects of Chemical Substances). Hamilton (Ont) : Canadian Centre for Occupational Health and Safety.   http://ccinfoweb.ccohs.ca/rtecs/search.html
• ▲2.  Centre canadien d'hygiène et de sécurité au travail, CHEMINFO, Hamilton, Ont. : Canadian Centre for Occupational Health and Safety   http://ccinfoweb.ccohs.ca/cheminfo/search.html
• ▲3.  France. Institut national de recherche et de sécurité, Fiche toxicologique no 128 : Cobalt et composés minéraux. Cahiers de notes documentaires. Paris : INRS. (2015). [RE-005509]   http://www.inrs.fr/publications/bdd/fichetox.html
  http://www.inrs.fr/publications/bdd/fichetox/fiche.html?refINRS=FICHETOX_128
• ▲4.  Agency for Toxic Substances and Diseases Registry (ATSDR), , Toxicological profile for cobalt.. ATSDR. Washington D.C. : US Department of Health and Human Services. (2004).   http://www.atsdr.cdc.gov/toxprofiles/index.asp#C http://www.atsdr.cdc.gov/ToxProfiles/tp33.pdf
• ▲5.  American Conference of Governmental Industrial Hygienists, Documentation of the threshold limit values and biological exposure indices / Documentation of TLV's and BEI's. 7th ed. Cincinnati, Ohio : ACGIH. (2001-). Publication #0100Doc. [RM-514008]   http://www.acgih.org
• ▲6.  IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, Cobalt in Hard-metals and Cobalt Sulfate, Gallium Arsenide, Indium Phosphide and Vanadium Pentoxide. IARC monographs on the evaluation of carinogenic risks to humans, Vol. 86. Lyon : International Agency for Research on Cancer. (2006).   http://monographs.iarc.fr/
  http://monographs.iarc.fr/ENG/Monographs/vol86/mono86.pdf
• ▲7.  Bucher J.R. et al., «Inhalation Toxicity Studies of Cobalt Sulfate in F344/N Rats and B6C3F1 Mice.» Fundamental and Applied Toxicology. Vol. 15, no. 2, p. 357-372. (1990). [AP-048354]
• ▲8.  Mohiuddin, S.M. et al., «Experimental cobalt cardiomyopathy.» American heart journal. Vol. 80, no. 4, p. 532-543. (Oct. 1970). [AP-001040]
• ▲9.  Morvai, V. et al., «The effects of simultaneous alcohol and cobalt chloride administration on the cardiovascular system of rats.» Acta physiologica Hungarica. Vol. 81, no. 3, p. 253-261. (1993). [AP-001041]
• ▲10.  Grice, H.C. et al., «Myocardial toxicity of cobalt in the rat.» Annals of the New York Academy of Sciences. Vol. 156, no. 1, p. 189-194. (Jan. 1969). [AP-001042]

The [number] refers to the Information SST database of the CNESST Documentation Center.