WHMIS (Picric acid)

Workplace Hazardous Materials Information System

WHMIS 2015 classification - Note to reader

• Combustible dusts - See comments below1 2

• Acute toxicity - oral - Category 33 4

• Skin corrosion/irritation - Category 13
• Strong acid: pH of a saturated solution = 1.21

• Serious eye damage/eye irritation - Category 13
• Forms a corrosive substance upon contact with water: 1.21

• Skin sensitization - Category 13 5 6 7 8 9 10

• Physical hazards not otherwise classified (exploding bomb) - Category 111 12 13

• Health hazards not otherwise classified (corrosion) - Category 1

Danger

Toxic if swallowed (H301)
Causes severe skin burns and eye damage (H314)
May cause allergic skin reaction (H317)
May cause an explosion under conditions of schock and/or friction
Causes severe damage to the respiratory tract

Ingredient disclosure

Comments:

This product could belong to the hazard class "Combustible dust", based on various factors related to the combustibility and explosiveness of its dust, including composition, shape and size of the particles.

References

• ▲1.  Dutch Institute for the Working Environment et Dutch Chemical Industry Association, Chemical safety sheets : working safely with hazardous chemicals. Netherlands : Kluwer Academic Publishers. (1991). [RR-015010]
• ▲2.  Combustion and explosion characteristics of dusts : BIA-Report 13/97. Sankt Ausgustin, Allemagne. (1997). [MO-127954]
• ▲3.  Centre canadien d'hygiène et de sécurité au travail, CHEMINFO, Hamilton, Ont. : Canadian Centre for Occupational Health and Safety   http://ccinfoweb.ccohs.ca/cheminfo/search.html
• ▲4.  Hobson, D.W., Serve, M.P. et Wyman, J.F., «Acute toxicity, distribution and metabolism of 2,4,6-trinitrophenol (picric acid) in Fischer rats..» Journal of Toxicology and Environmental Health. Vol. 37, p. 313-327. (1992).
• ▲5.  American Conference of Governmental Industrial Hygienists, Documentation of the threshold limit values and biological exposure indices / Documentation of TLV's and BEI's. 7th ed. Cincinnati, Ohio : ACGIH. (2001-). Publication #0100Doc. [RM-514008]   http://www.acgih.org
• ▲6.  Landsteiner, K. et di Somma, A.A., «Studies on the sensitization of animals with simple chemical compounds. VIII. Sensitization to picric acid; subsidiary agents and mode of sensitization.» Journal of Experimental Medicine. Vol. 72, p. 361-366. (1940). [AP-061282]
• ▲7.  Dennie, C.C., McBride, W.L. et Davis, P.E., «Toxic reactions produced by the application of trinitrophenol (picric acid).» Archives of Dermatology of Syphilology. Vol. 20, p. 698-704. (1929).
• ▲8.  Sulzberger, M.B. et Wise, F., «Drug eruptions. II. Dermatitis eczematosa due to drugs.» Archives of Dermatology and Syphilology. Vol. 28, no. 4, p. 461-474. (1933).
• ▲9.  Chase, M.W. et Maguire Jr., H.C., «Picric acid hypersensitivity : cross- reactivity and cellular transfer [Abstract].» Clinical Research. Vol. 29, p. 638. (1972).
• ▲10.  Schwartz, L., «Dermatitis from explosives.» The Journal of the American Medical Association. Vol. 125, no. 3, p. 186-190. (1944). [AP-019904]
• ▲11.  Vincoli, J.W., Risk management for hazardous chemicals : G-Z. Vol. 2. Boca Raton : Lewis Publishers. (1997). [RM-515112]
• ▲12.  Lewis Sr., R.J., Hazardous chemicals desk reference. 6 éd. Hoboken (New Jersey) : John Wiley & Sons Inc. (2008). [RM-515053]   www.wiley.com
• ▲13.  National Fire Protection Association, Fire protection guide to hazardous materials. 14th ed. Quincy, Mass. : NFPA. (2010). [RR-334001]

The [number] refers to the Information SST database of the CNESST Documentation Center.