WHMIS (Dinitrobenzene (all isomers) )

Workplace Hazardous Materials Information System

WHMIS 2015 classification - Note to reader

• Combustible dusts - See comments below1 2

• Specific target organ toxicity - single exposure - Category 13 4 5 6 7 8 9

• Specific target organ toxicity - repeated exposure - Category 14 6 7 9 10 11

• Physical hazards not otherwise classified (exploding bomb) - Category 11

Danger

Causes damage to organs (H370)
Causes damage to organs through prolonged or repeated exposure (H372)
May cause an explosion under conditions of schock and/or friction

Ingredient disclosure

Comments1 2 :

This product could belong to the hazard class "Combustible dust", based on various factors related to the combustibility and explosiveness of its dust, including composition, shape and size of the particles.

A thermally unstable substance liable to undergo a strongly exothermic decomposition. Laboratory testing performed on the substance as packaged is nescessary to determine the category (Type A to G) of this hazard class.

References

• ▲1.  Vincoli, J.W., Risk management for hazardous chemicals : A-F. Vol. 1. Boca Raton : Lewis Publishers. (1997). [RM-515112]
• ▲2.  Pohanish, R.P. et Greene, S.A., Wiley guide to chemical incompatibilities. 3ème éd. New Jersey : John Wiley & Sons Inc. (2009). [RR-015033]   www.wiley.com
• ▲3.  Linder R.E., Hess R.A. et Strader L.F., «Testicular Toxicity and Infertility in male Rats Treated with 1.3-Dinitrobenzene.» Journal of Toxicology and Environmental Health. Vol. 19, p. 477-489. (1986).
• ▲4.  «Toxicology Update.» Journal of Applied Toxicology. Vol. 9, no. 3, p. 199-202. (1989). [AP-034003]
• ▲5.  Blackburn D.M. et al., «A Comparaison of the Effetcts of the Three Isomers of Dinitrobenzene on the Testis in the Rat..» Toxicology and Applied Pharmacology. Vol. 92, p. 54-64. (1988).
• ▲6.  Lauwerys, R. et al., Toxicologie industrielle et intoxications professionnelles. 5ème éd. Issy-les-Moulineaux Cedex : Elsevier Masson SAS. (2007). [RM-514015]
• ▲7.  Okubo T. et Shigeta S, «Anemia Cases after Acute m-Dinitrobenzene Intoxication due to an Occupationnal Exposure.» Industrial Health. Vol. 20, p. 297-304. (1982).
• ▲8.  Philbert M.A. et al., «1.3-Dinitrobenzene-induced Encephalapathy in Rats.» Neuropathology and Applied Neurobiology. Vol. 13, p. 371-389. (1987). [AP-000484]
• ▲9.  Agency for Toxic Substances and Disease Registry, Toxicological profile for 1,3-Dinitrobenzene and 1,3,5-Trinitrobenzene. Atlanta, GA : ATSDR. (1995).   http://www.atsdr.cdc.gov/ToxProfiles/tp74.pdf
• ▲10.  Grant, W.M. et Schuman, J.S., Toxicology of the eye : effects on the eyes and visual systems from chemicals, drugs, metals and minerals, plants, toxins and venoms; also, systemic side effects from eye medications. Vol. 1, 4th ed. Springfield (ILL.) : Charles C. Thomas. (1993). [RM-515030]
• ▲11.  Bingham, E. et Cohrssen, B., Patty's toxicology. A Wiley-Interscience publication, 6ème éd. New York (NY) : John Wiley & Sons. (2012). [RM-214008]

The [number] refers to the Information SST database of the CNESST Documentation Center.