WHMIS (bis(4-Aminophenyl)methane)

Workplace Hazardous Materials Information System

WHMIS 2015 classification - Note to reader

• Combustible dusts - See comments below1 2 3

• Acute toxicity - oral - Category 41 4 5 6 7

• Acute toxicity - dermal - Category 25 6

• Skin sensitization - Category 11 6 7 8

• Carcinogenicity - Category 24 9 10

• Specific target organ toxicity - single exposure - Category 14 6 7 11

• Specific target organ toxicity - repeated exposure - Category 16 7

Danger

Harmful if swallowed (H302)
Fatal in contact with skin (H310)
May cause allergic skin reaction (H317)
Suspected of causing cancer (H351)
Causes damage to organs (H370)
Causes damage to organs through prolonged or repeated exposure (H372)

Ingredient disclosure

Comments: This product could belong to the hazard class "Combustible dust", based on various factors related to the combustibility and explosiveness of its dust, including composition, shape and size of the particles.

References

• ▲1.  Centre canadien d'hygiène et de sécurité au travail, CHEMINFO, Hamilton, Ont. : Canadian Centre for Occupational Health and Safety   http://ccinfoweb.ccohs.ca/cheminfo/search.html
• ▲2.  IFA-Gestis, Information system on hazardous substances of the German Social Accident Insurance. Sankt Augustin, Germany : Institut für Arbeitsschutz der Deutschen Gesetzlichen Unfallversicherung (IFA).   https://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
• ▲3.  New Jersey Department of Health and Senior Services, Hazardous substance fact sheet : 4,4'-Methylene dianiline. Right to Know Program. Trenton, NJ. (2001). RTK 1256.   www.state.nj.us/health/eoh/odisweb
• ▲4.  American Conference of Governmental Industrial Hygienists, Documentation of the threshold limit values and biological exposure indices / Documentation of TLV's and BEI's. 7th ed. Cincinnati, Ohio : ACGIH. (2001-). Publication #0100Doc. [RM-514008]   http://www.acgih.org
• ▲5.  National Institute for Occupational Safety and Health, RTECS (Registry of Toxic Effects of Chemical Substances). Hamilton (Ont) : Canadian Centre for Occupational Health and Safety.   http://ccinfoweb.ccohs.ca/rtecs/search.html
• ▲6.  France. Institut national de recherche et de sécurité, Fiche toxicologique no 218 : 4,4'-Diaminodiphénylméthane. Cahiers de notes documentaires. Paris : INRS. (2017). [RE-005509]   http://www.inrs.fr/publications/bdd/fichetox.html
  http://www.inrs.fr/publications/bdd/fichetox/fiche.html?refINRS=FICHETOX_218
• ▲7.  OECD, «4,4'-Methylenedianiline CAS N°: 101-77-9.» In: OECD Screening Information Data Set (SIDS) for High Production Volume Chemicals. Paris : UNEP Publications. (2001).   http://www.chem.unep.ch/irptc/sids/OECDSIDS/101779.pdf
• ▲8.  ECHA (European Chemicals Agency) , Information on chemicals (REACH)/ECHA chemicals database. Helsinki, Finland.   http://echa.europa.eu/information-on-chemicals/registered-substances
  https://chem.echa.europa.eu/
• ▲9.  Règlement sur la santé et la sécurité du travail [S-2.1, r. 13]. Québec : Éditeur officiel du Québec. [RJ-510071]   http://legisquebec.gouv.qc.ca/fr/ShowDoc/cr/S-2.1,%20r.%2013
• ▲10.  IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, Some chemicals used in plastics and elastomers. IARC monographs on the evaluation of the carcinogenic risk, Vol. 39. Lyon : International Agency for Research on Cancer. (1986).   https://monographs.iarc.fr/wp-content/uploads/2018/06/mono39.pdf
  http://www.iarc.fr
• ▲11.  Bingham, E., Cohrssen, B. et Powell, C.H., Patty's toxicology. A Wiley-Interscience publication, 5ème éd. New York (NY) : John Wiley & Sons. (2001). [RM-214008]

The [number] refers to the Information SST database of the CNESST Documentation Center.