WHMIS (Mercuric chromate)

Workplace Hazardous Materials Information System

WHMIS 2015 classification - Note to reader

• Respiratory sensitization - Category 11 2 3 4

• Skin sensitization - Category 1A4 5 6

• Carcinogenicity - Category 1A7 8

• Specific target organ toxicity - repeated exposure - Category 14 5 6 9 10 11 12 13

Danger

May cause allergy or asthma symptoms or breathing difficulties if inhaled (H334)
May cause allergic skin reaction (H317)
May cause cancer (H350)
Causes damage to organs through prolonged or repeated exposure (H372)

Ingredient disclosure

Comments:

This classification is based on all available data for insoluble hexavalent chromium (Cr VI) compounds.

Due to the lack of data, classification regarding specific organ toxicity - repeated exposure (H372) was established by analogy to inorganic mercury compounds (Mercury II chloride).

References

• ▲1.  Criteria group for occupational standards, «Scientific basis for Swedish occupational standards XXI. Consensus report for chromium and chromium compounds.» Arbete och Hälsa. Vol. VI, no. 22, p. 18-40. (2000). [AP-063399]   https://gupea.ub.gu.se/dspace/handle/2077/3194?locale=en
  http://www.inchem.org/documents/kemi/kemi/ah2000_22.pdf
• ▲2.  Asthmagen? : critical assessments of the evidence for agents implicated in occupational asthma. Health and Safety Executive. Sudbury, Suffolk, G.B. : HSE Books. (2001). [MO-020018]   http://www.hse.gov.uk/asthma/asthmagen.pdf
• ▲3.  Bernstein, I.L. et al., Asthma in the workplace : and related conditions. 3 éd. New York : Taylor & Francis. (2006).   www.taylorandfrancis.com
• ▲4.  Bureau européen des substances chimiques, European Union Risk Assessment Report : Chromium trioxide, sodium chromate, sodium dichromate, ammonium dichromate and potassium dichromate. 3rd Priority List, Vol. 53. Luxembourg : Office for Official Publications of the European Communities. (2005). EUR 21508 EN.   http://echa.europa.eu/documents/10162/3be377f2-cb05-455f-b620-af3cbe2d570b
• ▲5.  Agency for Toxic Substances and Disease Registry, Toxicological profile for chromium. Atlanta, GA : ATSDR. (2000). Microfiche : PB93-182434, ATSDR/TP-92/08   http://www.atsdr.cdc.gov/toxprofiles/
• ▲6.  Lauwerys, R. et al., Toxicologie industrielle et intoxications professionnelles. 5ème éd. Issy-les-Moulineaux Cedex : Elsevier Masson SAS. (2007). [RM-514015]
• ▲7.  American Conference of Governmental Industrial Hygienists, Documentation of the threshold limit values and biological exposure indices / Documentation of TLV's and BEI's. 7th ed. Cincinnati, Ohio : ACGIH. (2001-). Publication #0100Doc. [RM-514008]   http://www.acgih.org
• ▲8.  IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, A Review of Human Carcinogens: Arsenic, Metals, Fibres, and Dusts. IARC monographs on the evaluation of carcinogenic risks to humans, Vol. 100C. Lyon : International Agency for Research on Cancer. (2012).   http://monographs.iarc.fr/
  http://monographs.iarc.fr/ENG/Monographs/vol100C/mono100C.pdf
  
• ▲9.  Centre canadien d'hygiène et de sécurité au travail, CHEMINFO, Hamilton, Ont. : Canadian Centre for Occupational Health and Safety   http://ccinfoweb.ccohs.ca/cheminfo/search.html
• ▲10.  France. Institut national de recherche et de sécurité, Fiche toxicologique no 180 : Chromates et dichromates de sodium et potassium. Cahiers de notes documentaires. Paris : INRS. (2009). [RE-005509]   http://www.inrs.fr/publications/bdd/fichetox.html
  http://www.inrs.fr/publications/bdd/fichetox/fiche.html?refINRS=FICHETOX_180
• ▲11.  Uzzell BP et Oler J, «Chronic low-level mercury exposure and neurophysiological functioning.» Journal of Clinical and Experimental Neuropsychology . Vol. 8, p. 581-593. (1986).
• ▲12.  Agency for Toxic Substances and Disease Registry, Toxicological profile for mercury. Atlanta [GA] : ATSDR. (1999).   http://www.atsdr.cdc.gov/ http://www.atsdr.cdc.gov/ToxProfiles/tp46.pdf
• ▲13.  International Program on Chemical Safety, Elemental Mercury and Inorganic Mercury Compounds: Human Health Aspects. Concise International Chemical Assessment. Genève : World Health Organization. (2003). CICAD 50.   http://www.inchem.org/documents/cicads/cicads/cicad50.htm

The [number] refers to the Information SST database of the CNESST Documentation Center.