WHMIS (Nicotine)

Workplace Hazardous Materials Information System

WHMIS classification - Note to reader

• Acute toxicity - oral - Category 31 2 3 4 5 6 7 8

• Acute toxicity - dermal - Category 12 3 4 5 6

• Serious eye damage/eye irritation - Category 21 9 10

• Reproductive toxicity - Category 21 5 11
• Toxic to the development

• Specific target organ toxicity - single exposure - Category 11 5 6 7 11 12

Danger

Toxic if swallowed (H301)
Fatal in contact with skin (H310)
Causes serious eye irritation (H319)
Suspected of damaging fertility or the unborn child (H361)
Causes damage to organs (H370)

Ingredient disclosure

References

• ▲1.  American Conference of Governmental Industrial Hygienists, Documentation of the threshold limit values and biological exposure indices / Documentation of TLV's and BEI's. 7th ed. Cincinnati, Ohio : ACGIH. (2001-). Publication #0100Doc. [RM-514008]   http://www.acgih.org
• ▲2.  National Institute for Occupational Safety and Health, RTECS (Registry of Toxic Effects of Chemical Substances). Hamilton (Ont) : Canadian Centre for Occupational Health and Safety.   http://ccinfoweb.ccohs.ca/rtecs/search.html
• ▲3.  National Library of Medicine, The Hazardous Substances Data Bank (HSDB). Hamilton (Ont.) : Canadian Centre for Occupational Health and Safety.   http://www.ccohs.ca/
• ▲4.  Centre canadien d'hygiène et de sécurité au travail, CHEMINFO, Hamilton, Ont. : Canadian Centre for Occupational Health and Safety   http://ccinfoweb.ccohs.ca/cheminfo/search.html
• ▲5.  Bingham, E., Cohrssen, B. et Powell, C.H., Patty's toxicology. A Wiley-Interscience publication, 5ème éd. New York (NY) : John Wiley & Sons. (2001). [RM-214008]
• ▲6.  Krieger, R. et al., Handbook of pesticide toxicology : principles. Vol. 1, 2nd ed. New York : Academic Press. (2001). [RM-515024]
• ▲7.  Hayes, W.J., Pesticides studied in man. Baltimore : Williams & Wilkins. (1982). [MO-005384]
• ▲8.  Mayer, B, «How much nicotine kills a human? Tracing back the generally accepted lethal dose to dubious self-experiments in the nineteenth century .» Archives of Toxicology. Vol. 88, no. 1, p. 5-7. (2014).   http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880486/
• ▲9.  ECHA (European Chemicals Agency) , Information on chemicals (REACH)/ECHA chemicals database. Helsinki, Finland.   http://echa.europa.eu/information-on-chemicals/registered-substances
  https://chem.echa.europa.eu/
• ▲10.  Bingham, E., Cohrssen, B. et Powell, C.H., Patty's toxicology. A Wiley-Interscience publication. New York (Toronto) : John Wiley. (2001-). [RM-214008]   Patty's Toxicology | Major Reference Works
• ▲11.  IPCS (International Programme on Chemical Safety), Nicotine. ICSC #0519. IPCS, CEC. (1997).   http://www.inchem.org/documents/icsc/icsc/eics0519.htm
• ▲12.  Gosselin, R.E., Hodge, H.C. et Smith, R.P., Clinical toxicology of commercial products. 5e éd. Baltimore (MD) : Williams & Wilkins. (1984). [RM-514002]

The [number] refers to the Information SST database of the CNESST Documentation Center.