WHMIS (Nitrobenzene)

Workplace Hazardous Materials Information System

WHMIS 2015 classification - Note to reader

• Flammable liquids - Category 41
• Flash point = 88 °C Tag closed cup

• Acute toxicity - oral - Category 42 3 4 5 6

• Acute toxicity - dermal - Category 37

• Acute toxicity - inhalation - Category 37

• Carcinogenicity - Category 28 9

• Reproductive toxicity - Category 24 5 6 8 10 11
• Toxic to the reproductive function

• Specific target organ toxicity - single exposure - Category 14 5 6 8

• Specific target organ toxicity - repeated exposure - Category 14 5 8

Danger

Combustible liquid (H227)
Harmful if swallowed (H302)
Toxic in contact with skin (H311)
Toxic if inhaled (H331)
Suspected of causing cancer (H351)
Suspected of damaging fertility or the unborn child (H361)
Causes damage to organs (H370)
Causes damage to organs through prolonged or repeated exposure (H372)

Ingredient disclosure

References

• ▲1.  Pohanish, R.P. et Greene, S.A., Hazardous materials handbook. New York (NY) : Van Nostrand Reinhold. (1996). [RR-515125]
• ▲2.  National Institute for Occupational Safety and Health, RTECS (Registry of Toxic Effects of Chemical Substances). Hamilton (Ont) : Canadian Centre for Occupational Health and Safety.   http://ccinfoweb.ccohs.ca/rtecs/search.html
• ▲3.  Centre canadien d'hygiène et de sécurité au travail, CHEMINFO, Hamilton, Ont. : Canadian Centre for Occupational Health and Safety   http://ccinfoweb.ccohs.ca/cheminfo/search.html
• ▲4.  France. Institut national de recherche et de sécurité, Fiche toxicologique no 84 : Nitrobenzène. Cahiers de notes documentaires. Paris : INRS. (2007). [RE-005509]   http://www.inrs.fr/publications/bdd/fichetox.html
  http://www.inrs.fr/publications/bdd/fichetox/fiche.html?refINRS=FICHETOX_84
• ▲5.  Agency for Toxic Substances and Disease Registry, Toxicological profile for 1,3-dinitrobenzene and 1,3,5-trinitrobenzene. Atlanta, GA : ATSDR. (1995). Microfiche : PB95-264289   http://www.atsdr.cdc.gov/toxprofiles/
• ▲6.  International Program on Chemical Safety, Environmental Health Criteria 230: NITROBENZENE. Genève : World Health Organization. (2003). EHC198.   http://www.inchem.org/documents/ehc/ehc/ehc230.htm#7.1
• ▲7.  ECHA (European Chemicals Agency) , Information on chemicals (REACH)/ECHA chemicals database. Helsinki, Finland.   http://echa.europa.eu/information-on-chemicals/registered-substances
  https://chem.echa.europa.eu/
• ▲8.  American Conference of Governmental Industrial Hygienists, Documentation of the threshold limit values and biological exposure indices / Documentation of TLV's and BEI's. 7th ed. Cincinnati, Ohio : ACGIH. (2001-). Publication #0100Doc. [RM-514008]   http://www.acgih.org
• ▲9.  IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, Printing processes and printing inks, carbon black and some nitro compounds. IARC monographs on the evaluation of carcinogenic risks to humans, Vol. 65. Lyon : International Agency for Research on Cancer. (1996). [MO-018684]   https://monographs.iarc.fr/wp-content/uploads/2018/06/mono65.pdf
• ▲10.  German Research Foundation. Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area, List of MAK and BAT values 2017 : maximum concentrations and biological tolerance values at the workplace. Report / Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area ; 53 . Weinheim : Wiley-VCH. (2017).   http://www.dfg.de
  Fiche du Centre de documentation : https://www.centredoc.cnesst.gouv.qc.ca/in/details.xhtml?id=p%3A%3Ausmarcdef_0000220649
• ▲11.  Dodd, D. E., Fowler, E. H. et Snellings, W. M., «Reproduction and fertility evaluations in CD rats following nitrobenzene inhalation.» Fundamental and Applied Toxicology. Vol. 8, p. 493-505. (1987).

The [number] refers to the Information SST database of the CNESST Documentation Center.