WHMIS (2-Bromopropane)

Workplace Hazardous Materials Information System

WHMIS 2015 classification - Note to reader

• Flammable liquids - Category 21
• Flash point = 19 °C Setaflash closed cup and boiling point = 59 °C

• Reproductive toxicity - Category 1A2 3 4 5 6 7 8
• Toxic to the reproductive function

• Specific target organ toxicity - repeated exposure - Category 12 3 5 8 9 10

Danger

Highly flammable liquid and vapour (H225)
May damage fertility or the unborn child (H360)
Causes damage to organs through prolonged or repeated exposure (H372)

Ingredient disclosure

References

• ▲1.  Lenga, R.E. et Votoupal, K.L., The Sigma-Aldrich library of regulatory and safety data. Vol. 1. Milwaukee : Sigma-Aldrich. (1993). [RM-515040]
• ▲2.  American Conference of Governmental Industrial Hygienists, Documentation of the threshold limit values and biological exposure indices / Documentation of TLV's and BEI's. 7th ed. Cincinnati, Ohio : ACGIH. (2001-). Publication #0100Doc. [RM-514008]   http://www.acgih.org
• ▲3.  National Library of Medicine, The Hazardous Substances Data Bank (HSDB). Hamilton (Ont.) : Canadian Centre for Occupational Health and Safety.   http://www.ccohs.ca/
• ▲4.  Koh J.M. et al., «Primary ovarian failure caused by a solvent containing 2-bromopropane.» European journal of endocrinology. Vol. 138, p. 554-556. (1998). [AP-055354]
• ▲5.  Ichihara G., Asaeda N. et Kumazawa T., «Testicular and Hematopoietic Toxicity of 2-Bromopropane, a Substitute for Ozone Layer-depleting Chlorofluorocarbons..» Journal of Occupational Health. Vol. 39, p. 57-63. (1997).   https://www.jstage.jst.go.jp/article/joh1996/39/1/39_1_57/_pdf
• ▲6.  Kamijima M. et al., «Ovarian Toxicity of 2-Bromopropane in the Non-Pregnant Female Rat.» Journal of Occupational Health. Vol. 39, p. 144-149. (1997).   https://www.jstage.jst.go.jp/article/joh1996/39/2/39_2_144/_pdf
• ▲7.  Yu X. et al., «2-Bromopropane Causes Ovarian Dysfunction by Damaging Primordial Follicules and Their Oocytes in Female Rats.» Toxicology and Applied Pharmacology. Vol. 159, no. 3, p. 1999. (185-193).
• ▲8.  Park J.-S. et al., «An Outbreak of Hematopoietic and Reproductive Disorders Due to Solvents Containing 2-Bromopropane in an Electronic Factory, South Korea: Epidemiological Survey..» Journal of Occupational Health. Vol. 39, p. 138-143. (1997).   https://www.jstage.jst.go.jp/article/joh1996/39/2/39_2_138/_pdf
• ▲9.  ECHA (European Chemicals Agency) , Information on chemicals (REACH)/ECHA chemicals database. Helsinki, Finland.   http://echa.europa.eu/information-on-chemicals/registered-substances
  https://chem.echa.europa.eu/
• ▲10.  Kim Y. et al., «Hematopoietic and Reproductive Hazards of Korean Electronic Workers Exposed to Solvents Containing 2-Bromopropane.» Scandinavian Journal of Work, Environment & Health. Vol. 22, no. 5, p. 387-391. (1996).   http://www.sjweh.fi/show_abstract.php?abstract_id=159

The [number] refers to the Information SST database of the CNESST Documentation Center.