The section entitled Complete data sheet is not available in English for this substance. Consult the French version.

Identification

Description


Formule moléculaire brute : C12H7Cl3O2

Principaux synonymes

Noms français :

  • 2,4,4'-TRICHLORO-2'-HYDROXYDIPHENYL ETHER
  • 2,4,4'-TRICHLORO-2'-HYDROXYDIPHENYLETHER
  • 5-CHLORO-2-(2,4-DICHLOROPHENOXY) PHENOL
  • 5-CHLORO-2-(2,4-DICHLOROPHENOXY)-, PHENOL
  • 5-CHLORO-2-(2,4-DICHLOROPHENOXY)PHENOL
  • ETHER DE TRICHLORO-2,4,4' HYDROXY-2' DIPHENYL
  • ETHER, 2'-HYDROXY-2,4,4'-TRICHLORODIPHENYL
  • PHENOL, 5-CHLORO-2-(2,4-DICHLOROPHENOXY)-
  • PHENYL ETHER, 2'-HYDROXY-2,4,4'-TRICHLORO-
  • Éther de trichloro-2,4,4' hydroxy-2' diphényle
Utilisation et sources d'émission 1

Agent bactériostatique utilisé dans la fabrication de savons, détergents, pâte dentifrice et cosmétiques. Il est également incorporé à certaines fibres utilisées dans la fabrication de bas et de sous-vêtements.

Références

  • ▲1.  O’Neil, M.J., Smith, A. et Heckelman, P.E., The Merck index : an encyclopedia of chemicals, drugs, and biologicals. 13th ed. Cambridge, MA : Cambridge Soft; Merck & CO. (2001). [RM-403001]
  • ▲1.  O’Neil, M.J., Smith, A. et Heckelman, P.E., The Merck index : an encyclopedia of chemicals, drugs, and biologicals. 13th ed. Cambridge, MA : Cambridge Soft; Merck & CO. (2001). [RM-403001]
  • ▲2.  National Library of Medicine, The Hazardous Substances Data Bank (HSDB). Hamilton (Ont.) : Canadian Centre for Occupational Health and Safety.   http://www.ccohs.ca/
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  • ▲7.  Environment and Climate Change Canada et Health Canada, Assessment Report : Triclosan. (2016).   Cat (ec.gc.ca)
  • ▲8.  U.S. Food and Drug Administration et Department of Health and Human Services, Triclosan [CAS 3380-34-5] : Supporting Information for Toxicological Evaluation by the National Toxicology Program. Nomination Profile. (2008).   Nomination Background: Triclosan (CASRN: 3380-34-5) (nih.gov)
  • ▲9.  Weatherly, L.M. et Gosse, J.A., «Triclosan Exposure, Transformation, and Human Health effects.» Journal of Toxicology and Environmental Health - Part B - Critical Reviews. Vol. 20, no. 8, p. 447-469. (2017).   Triclosan Exposure, Transformation, and Human Health Effects (nih.gov)
  • ▲10.  National Industrial Chemicals Notification & Assessment Scheme, Triclosan. Priority existing chemical assessment report No. 30. Canberra, Australie : NICNAS. (2009).  

    PEC30-Triclosan.pdf (industrialchemicals.gov.au)


  • ▲11.  Rodricks, J.V. et al., «Triclosan: A critical review of the experimental data and development of margins of safety for consumer products.» Critical Reviews in Toxicology. Vol. 40, no. 5, p. 422-484. (2010).   Full article: Triclosan: A critical review of the experimental data and development of margins of safety for consumer products (tandfonline.com)
  • ▲12.  ECHA (European Chemicals Agency) , Information on Chemicals (REACH). Helsinki, Finland.  

    http://echa.europa.eu/information-on-chemicals/registered-substances
    ECHA CHEM (europa.eu)


  • ▲13.  SCCP (Scientific Committee on Consumer Products), Opinion on triclosan. (2009).   *Microsoft Word - opinion on P32 21 jan 09.doc (europa.eu)
  • ▲14.  American Conference of Governmental Industrial Hygienists, Documentation of the threshold limit values and biological exposure indices / Documentation of TLV's and BEI's. 7th ed. Cincinnati, Ohio : ACGIH. (2001-). Publication #0100Doc. [RM-514008]   http://www.acgih.org
  • ▲15.  Steinkjer, B. et Braathen, L.R., «Contact dermatitis from triclosan (Irgasan DP 300).» Contact Dermatitis. Vol. 18, p. 243-244. (1988).
  • ▲16.  Thune, P. et al., «The scandinavian multicenter photopatch study 1980-1985 : final report.» Photodermatology. Vol. 5, p. 261-269. (1988).
  • ▲17.  Veronesi, S. et al., «Contact dermatitis to triclosan.» Contact Dermatitis. Vol. 15, p. 257-258. (1986).
  • ▲18.  Perrenoud, D. et al., «Frequency of sensitization to 13 common preservatives in Switzerland.» Contact Dermatits. Vol. 30, p. 276-279. (1994).
  • ▲19.  Campbell, L. et Zirwas, M.J., «Triclosan.» Dermatitis. Vol. 17, no. 4, p. 204-207. (2006).
  • ▲20.  Wong, C.S.M. et Beck, M.H., «Allergic contact dermatitis from triclosan in antibacterial handwashes.» Contact Dermatitis. Vol. 45, no. 5, p. 307. (2001).
  • ▲21.  Roed-Petersen, J., Auken, G. et Hjorth, N., «Contact sensitivity to Irgasan DP 300.» Contact Dermatitis. Vol. 1, p. 293-294. (1975).
  • ▲22.  Durbize, E. et al., «Spectrum of cross-photosensitization in 18 consecutive patients with contact photoallergy to ketoprofen : associated photoallergies to non-benzophenone-containing molecules.» Contact Dermatitis. Vol. 48, no. 3, p. 144-149. (2003).
  • ▲23.  Lachapelle, J.M. et Tennstedt, D., «Low allergenicity of triclosan. Predictive testing in guinea pigs and in humans.» Dermatologica. Vol. 158, no. 5, p. 379-383. (1979).
  • ▲24.  Barbolt, T.A., «Chemistry and safety of triclosan, and its use as an antimicrobial coating on Coated Vicryl* Plus Antibacterial Suture (coated polyglactin 910 suture with triclosan).» Surgical Infections. Vol. 3, no. SUPPL. 1, p. S45-S53. (2002).
  • ▲25.  Wahlberg, J.E., «Routine patch testing with Irgasan DP 300.» Contact Dermatitis. Vol. 2, p. 292. (1976).
  • ▲26.  Gareth, I. W. et al., «Occupational asthma caused by sensitization to a cleaning product containing triclosan.» Annals of allergy, asthma and immunology. Vol. 118, no. 3, p. 370-371. (Mar. 2017). [AP-001149]
  • ▲27.  Schardein, J.L., Chemically induced birth defects. 3ème rév. & expanded. New York : Dekker. (2000). [MO-122294]
  • ▲28.  Piecacz, H., «Effects of certain preservative agents on the course of pregnancy and fetal development in experimental animals with preliminary toxicological characteristics.» Roczniki Panstwowego Zakladu Higieny. Vol. 29, no. 5, p. 469-481. (1978). [AP-049927]
  • ▲29.  Adolfsson-Erici, M. et al., «Triclosan, a commonly used bactericide found in human milk and in the aquatic environment in Sweden.» Chemosphere. Vol. 46, no. 9-10, p. 1485-1489. (2002). [AP-067455]
  • ▲30.  Dayan, A. D., «Risk assessment of triclosan [Irgasan] in human breast milk.» Food and Chemical Toxicology. Vol. 45, no. 1, p. 125-129. (2007).

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