• Complete data sheet (Available in French only)
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  • Summary

The information for this substance is partially available.

The section entitled Complete data sheet is not available in English for this substance. Consult the French version.

Identification

Description


Formule moléculaire brute : C9H10O3

Principaux synonymes

Noms français :

  • Anhydride de méthyl tétrahydrophtalique (MTHPA)
  • Anhydride méthyltétrahydrophtalique (MTHPA)
  • Anhydride tétrahydrométhylphtalique
  • Méthyltétrahydro-2-benzofurane-1,3-dione

Noms anglais :

  • 1,3-ISOBENZOFURANDIONE, TETRAHYDROMETHYL-
  • Methyl tetrahydrophthalic anhydride (MTHPA)
  • Methyl tetrahydropthalic anhydride
Utilisation et sources d'émission 1 2

L'anhydride méthyltétrahydrophtalique (MTHPA) est utilisé principalement comme agent de durcissement pour des résines époxy. Il est aussi utilisé dans des matériaux composites mis en oeuvre par enroulement filamentaire.

Références

  • ▲1.  Bohnet, M. et al., Ullmann's Encyclopedia of Industrial Chemistry. 7th. Wiley InterScience (John Wiley & Sons). (2003-).   http://www3.interscience.wiley.com (http://www3.interscience.wiley.com/cgi-bin/mrwhome/104554801/HOME)
  • ▲2.  OECD, «SIDS Initial Assessment Report for SIAM 15 - Tetrahydromethyl-1,3-isobenzofuranedione ( C.A.S : 11070-44-3).» In: OECD Screening Information Data Set (SIDS) . Paris : UNEP Publications. (2002).   http://www.inchem.org/documents/sids/sids/11070443.pdf
  • ▲2.  OECD, «SIDS Initial Assessment Report for SIAM 15 - Tetrahydromethyl-1,3-isobenzofuranedione ( C.A.S : 11070-44-3).» In: OECD Screening Information Data Set (SIDS) . Paris : UNEP Publications. (2002).   http://www.inchem.org/documents/sids/sids/11070443.pdf
  • ▲2.  OECD, «SIDS Initial Assessment Report for SIAM 15 - Tetrahydromethyl-1,3-isobenzofuranedione ( C.A.S : 11070-44-3).» In: OECD Screening Information Data Set (SIDS) . Paris : UNEP Publications. (2002).   http://www.inchem.org/documents/sids/sids/11070443.pdf
  • ▲3.  ECHA (European Chemicals Agency) , Information on Chemicals (REACH). Helsinki, Finland.  

    http://echa.europa.eu/information-on-chemicals/registered-substances
    ECHA CHEM (europa.eu)


  • ▲3.  ECHA (European Chemicals Agency) , Information on Chemicals (REACH). Helsinki, Finland.  

    http://echa.europa.eu/information-on-chemicals/registered-substances
    ECHA CHEM (europa.eu)


  • ▲4.  BGIA-Gestis, Information system on hazardous substances of the Berufsgenossenschaften. Sankt Augustin, Germany : Berufsgenossenschaftliches Institut.   http://gestis-database.dguv.de
  • ▲5.  National Industrial Chemicals Notification & Assessment Scheme, Tetrahydrophthalic anhydrides and analogues: Human health tier II assessment. Inventory multi-tiered assessment and prioritisation (IMAP). Sydney, Australie : NICNAS. (2018).   https://www.nicnas.gov.au/chemical-information/imap-assessments/imap-group-assessment-report?assessment_id=10266#cas-A_11070-44-3
  • ▲6.  Welinder, H. et al., «Decline in serum antibodies to methyltetrahydrophthalic anhydride after cessation of exposure. Implications for use as a biomarker.» Biomarkers. Vol. 3, no. 2, p. 141-148. (1998).
  • ▲7.  Yokota, K. et al., «The significance of specific IgG4 antibodies to methyltetrahydrophthalic anhydride in occupationally exposed subjects.» Clinical and Experimental Allergy. Vol. 28, no. 6, p. 694-701. (1998).
  • ▲8.  Yokota, K. et al., «Study on allergic rhinitis in workers exposed to methyltetrahydrophthalic anhydride.» Environmental Health and Preventive Medicine. Vol. 1, no. 3, p. 133-135. (1996).
  • ▲9.  Yokota, K. et al., «Risk factors for sensitization to methyltetrahydrophthalic anhydride.» Occupational and Environmental Medicine. Vol. 54, no. 9, p. 667-670. (1997).
  • ▲10.  Tarvainen, K. et al., «Immunologic contact urticaria due to airborne methylhexahydrophthalic and methyltetrahydrophthalic anhydrides.» Contact Dermatitis. Vol. 32, p. 204-209. (1995). [AP-022685]
  • ▲11.  Drexler, H. et al., «Detection and clinical relevance of a type I allergy with occupational exposure to hexahyrophthalic anhydride and methyltetrahydrophthalic anhydride.» International Archives of Occupational and Environmental Health. Vol. 65, p. 279-283. (1994).
  • ▲12.  Yokota, K. et al., «Exposure-response relationship in rhinitis and conjunctivitis caused by methyltetrahydrophthalic anhydride.» International Archives of Occupational and Environmental Health. Vol. 72, p. 14-18. (1999).
  • ▲13.  Nielsen, J., Welinder, H. et Skerfving, S., «Allergic airway disease caused by methyl tetrahydrophthalic anhydride in epoxy resin.» Scandinavian Journal of Work, Environment & Health. Vol. 15, p. 154-155. (1989).
  • ▲14.  Yokota, K. et al., «Specific antibodies against methyltetrahydrophthalic anhydride and risk factors for sensitization in occupationally exposed subjects.» Scandinavian Journal of Work, Environment & Health. Vol. 23, p. 214-220. (1997).
  • ▲15.  Nielsen, J. et al., «Allergy to methyltetrahydrophthalic anhydride in epoxy resin workers.» British Journal of Industrial Medicine. Vol. 49, p. 769-775. (1992).
  • ▲16.  Kalimo, K. et al., «IgE-mediated allergy to methyltetrahydrophthalic anhydride among workers producing electrical components.» Contact Dermatitis. Vol. 23, p. 280. (1990).
  • ▲17.  American Conference of Governmental Industrial Hygienists, «Methyltetrahydrophthalic anhydride isomers.» In: Documentation of the threshold limit values and biological exposure indices / Documentation of TLV's and BEI's. Cincinnati, Ohio : ACGIH. (2019). Publication #0100Doc.   http://www.acgih.org
  • ▲18.  Welinder, H. et Nielsen, J., «Immunologic tests of specific antibodies to organic acid anhydrides.» Allergy. Vol. 46, p. 601-609. (1991). [AP-036844]

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