WHMIS (Nickel carbonyl)

Workplace Hazardous Materials Information System

WHMIS 2015 classification - Note to reader

• Flammable liquids - Category 21
• Flash point < -20 °C closed cup (non reported method) and boiling point = 43 °C

• Acute toxicity - inhalation - Category 12 3

• Carcinogenicity - Category 1A4 5

• Reproductive toxicity - Category 24 6 7 8 9

• Specific target organ toxicity - repeated exposure - Category 13 4 8 10

Danger

Highly flammable liquid and vapour (H225)
Fatal if inhaled (H330)
May cause cancer (H350)

Ingredient disclosure

References

• ▲1.  National Fire Protection Association, Fire protection guide to hazardous materials. 14th ed. Quincy, Mass. : NFPA. (2010). [RR-334001]
• ▲2.  Centre canadien d'hygiène et de sécurité au travail, CHEMINFO, Hamilton, Ont. : Canadian Centre for Occupational Health and Safety   http://ccinfoweb.ccohs.ca/cheminfo/search.html
• ▲3.  National research council, «Nickel Carbonyl.» In: Acute Exposure Guideline Levels for Selected Airborne Chemicals: Volume 6. , p. 177-209. Washington : National acedemies press. (2008).   http://www.nap.edu/catalog/12018/acute-exposure-guideline-levels-for-selected-airborne-chemicals-volume-6
• ▲4.  American Conference of Governmental Industrial Hygienists, 2022 TLVs and BEIs with 7th edition documentation CD-ROM. Cincinnati, OH : ACGIH. (2022). Publication 0111CD. [CD-120061]   http://www.acgih.org
• ▲5.  IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, A Review of Human Carcinogens: Arsenic, Metals, Fibres, and Dusts. IARC monographs on the evaluation of carcinogenic risks to humans, Vol. 100C. Lyon : International Agency for Research on Cancer. (2012).   http://monographs.iarc.fr/
  http://monographs.iarc.fr/ENG/Monographs/vol100C/mono100C.pdf
  
• ▲6.  Sunderman, F.W. , Allpass, P.R. et Mitchell, J.M. , «Eye malformations in rats : induction by prenatal exposure to nickel carbonyl.» Science. Vol. 203, p. 550-553. (1979). [AP-037121]
• ▲7.  Sunderman, F.W. et al., «Teratogenicity and embryotoxicity of nickel carbonyl in Syrian hamsters.» Annals of Clinical and Laboratory Science. Vol. 11, p. 84. (1981). [AP-037195]
• ▲8.  Patty, F.A., Harris, R.L. et Ayer, H.E., Patty's industrial hygiene. A Wiley-Interscience publication, 5th ed. New York ; Toronto : John Wiley & Sons. (2000). [RM-214007]
• ▲9.  Health council of the Netherlands: Committee for compounds toxic to reproduction, «Nickel and its compounds. Evaluation of the effects on reproduction, recommendation for classification.» In: The Hague: Health Concil of the Netherlands. Vol. 05, p. 77. (2003).   http://www.gezondheidsraad.nl/en https://www.gezondheidsraad.nl/en/task-and-procedure/areas-of-activity/healthy-working-conditions/nickel-and-its-compounds
• ▲10.  Lauwerys, R. et al., Toxicologie industrielle et intoxications professionnelles. 5ème éd. Issy-les-Moulineaux Cedex : Elsevier Masson SAS. (2007). [RM-514015]

The [number] refers to the Information SST database of the CNESST Documentation Center.