WHMIS (Pentachlorophenol)

Workplace Hazardous Materials Information System

WHMIS 2015 classification - Note to reader

• Acute toxicity - oral - Category 31 2 3 4 5

• Acute toxicity - dermal - Category 21 3 5

• Serious eye damage/eye irritation - Category 2B1 2 5 6

• Carcinogenicity - Category 21 7

• Reproductive toxicity - Category 1B1 2 3 4 8
• Toxic to the development

• Specific target organ toxicity - single exposure (respiratory tract irritation) - Category 3 - Respiratory tract irritation1 2

• Specific target organ toxicity - repeated exposure - Category 21 2 4 9 10

Danger

Toxic if swallowed (H301)
Fatal in contact with skin (H310)
Causes eye irritation (H320)
Suspected of causing cancer (H351)
May damage fertility or the unborn child (H360)
May cause respiratory irritation (H335)
May cause damage to organs through prolonged or repeated exposure (H373)

Ingredient disclosure

References

• ▲1.  American Conference of Governmental Industrial Hygienists, Documentation of the threshold limit values and biological exposure indices / Documentation of TLV's and BEI's. 7th ed. Cincinnati, Ohio : ACGIH. (2001-). Publication #0100Doc. [RM-514008]   http://www.acgih.org
• ▲2.  France. Institut national de recherche et de sécurité, Fiche toxicologique no 11 : Pentachlorophénol et sel de sodium. Cahiers de notes documentaires. Paris : INRS. (1997).   http://www.inrs.fr/publications/bdd/fichetox.html
  http://www.inrs.fr/publications/bdd/fichetox/fiche.html?refINRS=FICHETOX_11
• ▲3.  International Programme on Chemical Safety, Environmental Health Criteria 71: Pentachlorophenol. Genève : World Health Organization. (1987). EHC71. [MO-011735]   http://www.inchem.org/pages/ehc.html
• ▲4.  Agency for Toxic Substances and Disease Registry, Toxicological profile for pentachlorophenol. Atlanta, GA : ATSDR. (1989). Draft for public comment. Microfiche : PB90-182163, ATSDR/TP-89/19   http://www.atsdr.cdc.gov/toxprofiles/
• ▲5.  FIELDER, R.J. , PENTACHLOROPHENOL. Health and Safety Executive . LONDON : H.M.S.O.. (1982). [MO-003929 ]
• ▲6.  Younger Laboratories, Initial submission : toxicological investigation of pentachlorophenol with cover letter dated 081392. Saint Louis, Missouri. (1975). Microfiche : OTS0570564, EPA/OTS; Doc #88-920007950
• ▲7.  IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, Re-evaluation of some organic chemicals, hydrazine and hydrogen peroxide : part 1. IARC monographs on the evaluation of carcinogenic risks to humans, Vol. 71. Lyon : International Agency for Research on Cancer. (1999).   https://monographs.iarc.fr/wp-content/uploads/2018/06/mono71.pdf http://www.iarc.fr
• ▲8.  Schwetz, B.A., Keeler, P.A. et Gehring, P.J., «The effect of purified and commercial grade pentachlorophenol on rat embryonal and fetal development.» Toxicology and Applied Pharmacology. Vol. 28, p. 151-161. (1974). [AP-005892]
• ▲9.  Report on Carcinogens, 15th edition. Research Triangle Park, NC : U.S. Department of Health and Human Services, Public Health Service, National Toxicology Program. (2021).   https://ntp.niehs.nih.gov/pubhealth/roc/index-1.html
• ▲10.  Chhabra, R. S., Maronpot, R. M. et Bucher, J. R., «Toxicology and carcinogenesis studies of pentachlorophenol in rats.» Toxicological Sciences. Vol. 48, p. 14-20. (1999).

The [number] refers to the Information SST database of the CNESST Documentation Center.