WHMIS (o-Chlorobenzylidene malononitrile)

Workplace Hazardous Materials Information System

WHMIS 2015 classification - Note to reader

• Combustible dusts - See comments below1

• Acute toxicity - oral - Category 42 3 4 5

• Skin corrosion/irritation - Category 25 6 7 8

• Serious eye damage/eye irritation - Category 25 6 7 8

• Skin sensitization - Category 16 9 10 11 12 13 14

• Specific target organ toxicity - single exposure (respiratory tract irritation) - Category 3 - Respiratory tract irritation6

Warning

Harmful if swallowed (H302)
Causes skin irritation (H315)
Causes serious eye irritation (H319)
May cause allergic skin reaction (H317)
May cause respiratory irritation (H335)

Ingredient disclosure

Comments: This product could belong to the hazard class "Combustible dust", based on various factors related to the combustibility and explosiveness of its dust, including composition, shape and size of the particles.

References

• ▲1.  Pohanish, R.P., Sittig's handbook of toxic and hazardous chemicals and carcinogens. 6th ed. Amsterdam : William Andrew. (2012). [RR-015003]   https://www.sciencedirect.com/book/9781437778694/sittigs-handbook-of-toxic-and-hazardous-chemicals-and-carcinogens
• ▲2.  National Institute for Occupational Safety and Health, RTECS (Registry of Toxic Effects of Chemical Substances). Hamilton (Ont) : Canadian Centre for Occupational Health and Safety.   http://ccinfoweb.ccohs.ca/rtecs/search.html
• ▲3.  Centre canadien d'hygiène et de sécurité au travail, CHEMINFO, Hamilton, Ont. : Canadian Centre for Occupational Health and Safety   http://ccinfoweb.ccohs.ca/cheminfo/search.html
• ▲4.  France. Institut national de recherche et de sécurité, Fiche toxicologique no 215 : o-Chlorobenzylidènemalononitrile. Cahiers de notes documentaires. Paris : INRS. (1987). [RE-005509]   http://www.inrs.fr/publications/bdd/fichetox.html
  http://www.inrs.fr/publications/bdd/fichetox/fiche.html?refINRS=FICHETOX_215
• ▲5.  Gaskins, J.R. et al., «Lacrimating agents (CS and CN) in rats and rabbits.» Archives of Environmental Health. Vol. 24, p. 449-454. (1972). [AP-020031]
• ▲6.  American Conference of Governmental Industrial Hygienists, Documentation of the threshold limit values and biological exposure indices / Documentation of TLV's and BEI's. 7th ed. Cincinnati, Ohio : ACGIH. (2001-). Publication #0100Doc. [RM-514008]   http://www.acgih.org
• ▲7.  Ballantyne, B. et Swanston, D.W., «The comparative acute mammalian toxicity of 1-chloroacetophenone (CN) and 2-chlorobenzylidene malonitrile.» Archives of Toxicology. Vol. 40, p. 75-95. (1978). [AP-022346]
• ▲8.  Ballantyne, B., «Acute toxicity and primary irritancy of 2-amino-3,5-dicyano-4-o-chlorophenyl-6-ethopyridine.» Drug and Chemical Toxicology. Vol. 8, no. 3, p. 171-182. (1985). [AP-013276]
• ▲9.  Fuchs, V.T. et Ippen, H., «Kontaktallergie auf CN- und CS-tränengas.» Dermatosen in Beruf und Umwelt. Vol. 34, no. 1, p. 12-14. (1986). [AP-013596]
• ▲10.  Kanerva, L. et al., «A single accidental exposure may result in a chemical burn, primary sensitization and allergic contact dermatitis.» Contact Dermatitis. Vol. 31, p. 229-235. (1994).
• ▲11.  Chung, C.W. et Giles, A.L., «Sensitization of guinea pigs to alpha-chloroacetophenone (CN) and ortho-chlorobenzylidenemalonitrile (CS), tear gas chemicals.» Journal of Immunology. Vol. 109, no. 2, p. 284-293. (1972). [AP-021032]
• ▲12.  Rothberg, S., «Skin sensitization potential of the riot control agents BBC, DM, CN and CS in guinea pigs.» Military Medicine. Vol. 135, no. 7, p. 552-556. (1970). [AP-062514]
• ▲13.  Sommer, S. et Wilkinson, S.M., «Exposure-pattern dermatitis due to CS gas.» Contact Dermatitis. Vol. 40, no. 1, p. 46-47. (1999). [AP-062513]
• ▲14.  Shmunes, E. et Taylor, J.S., «Industrial contact dermatitis - Effect of the riot control agent ortho-chlorobenzylidene malonitrile.» Archives of Dermatology. Vol. 107, p. 212-216. (1973). [AP-014139]

The [number] refers to the Information SST database of the CNESST Documentation Center.