WHMIS (Nitrogen dioxide)

Workplace Hazardous Materials Information System

WHMIS 2015 classification - Note to reader

• Oxidizing gases - Category 11 2
• Gas listed in ISO 10156:2010 standard

• Gases under pressure - Liquefied gas3
• Liquified gas, listed in : UN Recommendations on the TDG - Model Regulations Vol II.

• Acute toxicity - inhalation - Category 14 5 6 7

• Skin corrosion/irritation - Category 24 8

• Serious eye damage/eye irritation - Category 18 9

• Germ cell mutagenicity - Category 210 11 12

• Specific target organ toxicity - repeated exposure - Category 14

• Health hazards not otherwise classified (corrosion) - Category 14 5 6 8

Danger

May cause or intensify fire; oxidizer (H270)
Contains gas under pressure; may explode if heated (H280)
Fatal if inhaled (H330)
Causes skin irritation (H315)
Causes serious eye damage (H318)
Suspected of causing genetic defects (H341)
Causes damage to organs through prolonged or repeated exposure (H372)
Causes severe damage to the respiratory tract

Ingredient disclosure

References

• ▲1.  Vincoli, J.W., Risk management for hazardous chemicals : G-Z. Vol. 2. Boca Raton : Lewis Publishers. (1997). [RM-515112]
• ▲2.  Organisation internationale de normalisation, Gaz et mélanges de gaz : détermination du potentiel d'inflammabilité et d'oxydation pour le choix des raccords de sortie de robinets.. ISO: 10156:2010, 3e éd.. Genève : Organisation internationale de normalisation. (2010). [NO-001791]
• ▲3.  Nations-Unies, «Partie 4 - Dispositions relatives à l'utilisation des emballages et des citernes - Liste des instructions d'emballage.» In: Recommandations relatives au transport des marchandises dangereuses - Règlement type - Dix-huitième édition révisée . New-York, N.Y. : United Nations. (2013). ST/SG/AC.10/1/rev. 18 (Vol. II). [MO-026856]   http://www.unece.org/fileadmin/DAM/trans/danger/publi/unrec/rev18/French/Rev18f_Volume2.pdf
  http://www.unece.org/fr/trans/danger/publi/unrec/rev18/18files_f.html
• ▲4.  Centre canadien d'hygiène et de sécurité au travail, CHEMINFO, Hamilton, Ont. : Canadian Centre for Occupational Health and Safety   http://ccinfoweb.ccohs.ca/cheminfo/search.html
• ▲5.  France. Institut national de recherche et de sécurité, Fiche toxicologique no 133 : Monoxyde d'azote. Peroxyde d'azote. Cahiers de notes documentaires. Paris : INRS. (2006). [RE-005509]   http://www.inrs.fr/publications/bdd/fichetox.html
  http://www.inrs.fr/publications/bdd/fichetox/fiche.html?refINRS=FICHETOX_133
• ▲6.  Institut national de l'environnement industriel et des risques (INERIS), Fiche de données toxicologiques et environnementales des substances chimiques. Oxydes d'azote NOx. (2005).   http://www.ineris.fr/ Dans Rapports d'étude, Toxicologie et environnement, Fiche de données
• ▲7.  CARSON, T.R. et al., «THE RESPONSES OF ANIMALS INHALING NITROGEN DIOXIDE FOR SINGLE, SHORT-TERM EXPOSURES .» Industrial hygiene journal. Vol. 23, p. 457-462 . (1962).
• ▲8.  American Conference of Governmental Industrial Hygienists, Documentation of the threshold limit values and biological exposure indices / Documentation of TLV's and BEI's. 7th ed. Cincinnati, Ohio : ACGIH. (2001-). Publication #0100Doc. [RM-514008]   http://www.acgih.org
• ▲9.  Grant, W.M. et Schuman, J.S., Toxicology of the eye : effects on the eyes and visual systems from chemicals, drugs, metals and minerals, plants, toxins and venoms; also, systemic side effects from eye medications. Vol. 1, 4th ed. Springfield (ILL.) : Charles C. Thomas. (1993). [RM-515030]
• ▲10.  Isomura, K. et al., «Induction of mutations and chromosome aberrations in lung cells following in vivo exposure of rats to nitrogen oxides.» Mutation research. Vol. 136, no. 4, p. 119-125. (1984). [AP-020673]
• ▲11.  Victorin, K., «Review of the genotoxicity of nitrogen oxides.» Mutation Research. Vol. 317, no. 1, p. 43-55. (1994). [AP-044416]
• ▲12.  Han, M., Guo, Z. et Sang, N., «Nitrogen dioxide inhalation induces genotoxicity in rats.» Chemosphere. Vol. 90, no. 11, p. 2737-2742. (2013).

The [number] refers to the Information SST database of the CNESST Documentation Center.