WHMIS (Cobalt dichloride)

Workplace Hazardous Materials Information System

WHMIS 2015 classification - Note to reader

• Acute toxicity - oral - Category 41

• Serious eye damage/eye irritation - Category 21

• Respiratory sensitization - Category 11 2 3 4

• Skin sensitization - Category 15

• Carcinogenicity - Category 26

• Specific target organ toxicity - repeated exposure - Category 17 8 9 10

Danger

Harmful if swallowed (H302)
Causes serious eye irritation (H319)
May cause allergy or asthma symptoms or breathing difficulties if inhaled (H334)
May cause allergic skin reaction (H317)
Suspected of causing cancer (H351)
Causes damage to organs through prolonged or repeated exposure (H372)

Ingredient disclosure

References

• ▲1.  ECHA (European Chemicals Agency) , Information on chemicals (REACH)/ECHA chemicals database. Helsinki, Finland.   http://echa.europa.eu/information-on-chemicals/registered-substances
  https://chem.echa.europa.eu/
• ▲2.  Kusaka, Y. et al., «Respiratory diseases in hard metal workers : an occupational hygiene study in a factory.» British Journal of Industrial Medicine. Vol. 43, p. 474-485. (1986). [AP-013249]
• ▲3.  Shirakawa, T. et al., «The existence of specific antibodies to cobalt in hard metal asthma.» Clinical Allergy. Vol. 18, no. 5, p. 451-460. (1988). [AP-068447]
• ▲4.  Shirakawa, T. et al., «Occupational asthma from cobalt sensivity in workers exposed to hard metal dust.» Chest. Vol. 95, no. 1, p. 29-37. (1989). [AP-024259]
• ▲5.  France. Institut national de recherche et de sécurité, Fiche toxicologique no 128 : Cobalt et composés minéraux. Cahiers de notes documentaires. Paris : INRS. (2015). [RE-005509]   http://www.inrs.fr/publications/bdd/fichetox.html
  http://www.inrs.fr/publications/bdd/fichetox/fiche.html?refINRS=FICHETOX_128
• ▲6.  IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, Chlorinated drinking-water; chlorination by-products; so other halogenated compounds; cobalt and cobalt compounds. IARC monographs on the evaluation of carcinogenic risks to humans, Vol. 52. Lyon : International Agency for Research on Cancer. (1991).   https://monographs.iarc.fr/wp-content/uploads/2018/06/mono52.pdf
• ▲7.  Agency for Toxic Substances and Diseases Registry (ATSDR), , Toxicological profile for cobalt.. ATSDR. Washington D.C. : US Department of Health and Human Services. (2004).   http://www.atsdr.cdc.gov/toxprofiles/index.asp#C http://www.atsdr.cdc.gov/ToxProfiles/tp33.pdf
• ▲8.  Mohiuddin, S.M. et al., «Experimental cobalt cardiomyopathy.» American heart journal. Vol. 80, no. 4, p. 532-543. (Oct. 1970). [AP-001040]
• ▲9.  Morvai, V. et al., «The effects of simultaneous alcohol and cobalt chloride administration on the cardiovascular system of rats.» Acta physiologica Hungarica. Vol. 81, no. 3, p. 253-261. (1993). [AP-001041]
• ▲10.  Grice, H.C. et al., «Myocardial toxicity of cobalt in the rat.» Annals of the New York Academy of Sciences. Vol. 156, no. 1, p. 189-194. (Jan. 1969). [AP-001042]

The [number] refers to the Information SST database of the CNESST Documentation Center.