The section entitled For a Maternity Experience program is not available in English for this substance. Consult the French version.

Programme pour une maternité sans danger (PMSD)

Propriétés physiques pertinentes 1 2 3 4 5 6 7 8 9

Mise à jour : 2021-02-15

Voies d'absorption

L'information relative à cette section n'est pas disponible actuellement.

Effets sur le développement

L'information relative à cette section n'est pas disponible actuellement

Effets sur la reproduction

L'information relative à cette section n'est pas disponible actuellement

Effets sur l'allaitement

L'information relative à cette section n'est pas disponible actuellement

Cancérogénicité 10 11 12

Mise à jour : 2013-01-17

Évaluation de la cancérogénicité par des organismes officiels

Le Centre international de recherche sur le cancer (CIRC, 2012) considère l'ortho-nitrotoluène comme étant probablement cancérogène pour l'homme (groupe 2A).

Le NTP (2011) considère l'ortho-nitrotoluène comme étant raisonnablement anticipée cancérogène chez l'humain (R).

Mutagénicité

L'information relative à cette section n'est pas disponible actuellement.

Références

• ▲1.  National Institute for Occupational Safety and Health, NIOSH pocket guide to chemical hazards. 3 ed. Cincinnati, Ohio : NIOSH. (2007). [RM-514001]   https://www.cdc.gov/niosh/npg/default.html
• ▲2.  American Conference of Governmental Industrial Hygienists, «Nitrotoluene (all isomers) CAS 88-72-2 (ortho), 99-08-1 (meta), 99-99-0 (para).» In: Documentation of the threshold limit values and biological exposure indices / Documentation of TLV's and BEI's. Cincinnati, Ohio : ACGIH. (2001). Publication #0100Doc.   http://www.acgih.org
• ▲3.  Lewis, R.J., Sr., Hawley's condensed chemical dictionary. 15th ed. Hoboken : John Wiley & Sons. (2007). [RS-407001]   http://onlinelibrary.wiley.com/book/10.1002/9780470114735
• ▲4.  O'Neil, M.J. et al., The Merck Index : an encyclopedia of chemicals, drugs, & biologicals. 15e éd. Cambridge, G.-B. : Royal Society of Chemistry. (2013). [RM-403001]   https://www.rsc.org/Merck-Index/
• ▲5.  Kroschwitz, J.I., Kirk-Othmer encyclopedia of chemical technology. 5th ed. Hoboken, N.J. : John Wiley & Sons. (2004-). [RT-423004]
• ▲6.  Bingham, E., Cohrssen, B. et Powell, C.H., Patty's toxicology. A Wiley-Interscience publication. New York (Toronto) : John Wiley. (2001-). [RM-214008]   http://www3.interscience.wiley.com (http://www3.interscience.wiley.com/cgi-bin/mrwhome/104554795/HOME)
• ▲7.  Haynes, W.M., Bruno, T.J. et Lide, D.R., CRC handbook of chemistry and physics, 2016-2017. 97th ed. Boca Raton (FL) : CRC Press. (2016). [RS-014001]   http://www.hbcpnetbase.com/
• ▲8.  Pohanish, R.P., Sittig's handbook of toxic and hazardous chemicals and carcinogens. Vol. 1 à 3, 7th ed. Oxford, G.-B : William Andrew Applied Science Publishers/Elsevier. (2017). [RR-015003]   https://www.sciencedirect.com/book/9781437778694/sittigs-handbook-of-toxic-and-hazardous-chemicals-and-carcinogens
• ▲9.  Bohnet, M. et al., Ullmann's Encyclopedia of Industrial Chemistry. 7th. Wiley InterScience (John Wiley & Sons). (2003-).   http://www3.interscience.wiley.com (http://www3.interscience.wiley.com/cgi-bin/mrwhome/104554801/HOME)
• ▲10.  IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, Printing processes and printing inks, carbon black and some nitro compounds. IARC monographs on the evaluation of carcinogenic risks to humans, Vol. 65. Lyon : International Agency for Research on Cancer. (1996). [MO-018684]   https://monographs.iarc.fr/wp-content/uploads/2018/06/mono65.pdf
• ▲11.  IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, A Review of Human Carcinogens: Some chemicals in industrial and consumer products, food contaminants and flavourings, and water chlorination by-products. IARC monographs on the evaluation of carcinogenic risks to humans, Vol. 101. Lyon : International Agency for Research on Cancer. (2012).   http://monographs.iarc.fr/
  http://monographs.iarc.fr/ENG/Monographs/vol101/index.php
• ▲12.  Report on Carcinogens, 15th edition. Research Triangle Park, NC : U.S. Department of Health and Human Services, Public Health Service, National Toxicology Program. (2021).   https://ntp.niehs.nih.gov/pubhealth/roc/index-1.html

Autres sources d'information

• National Institute for Occupational Safety and Health, NIOSH pocket guide to chemical hazards. 3 ed. Cincinnati, Ohio : NIOSH. (2007). [RM-514001]   https://www.cdc.gov/niosh/npg/default.html
• American Conference of Governmental Industrial Hygienists, 2022 TLVs and BEIs with 7th edition documentation CD-ROM. Cincinnati, OH : ACGIH. (2022). Publication 0111CD. [CD-120061]   http://www.acgih.org
• Lide, D.R. , CRC handbook of chemistry and physics. 73rd ed. Boca Raton, Fla : CRC Press. (1992).
• Mark, H.F., Grayson, M. et Eckroth, D., Kirk-Othmer encyclopedia of chemical technology. 3rd ed. New York : Wiley. (1978-84). [RT-423004]
• Lewis, R.J., Sax's dangerous properties of industrial materials. Vol. 1, 8ème éd. New York : Van Nostrand Reinhold. (1992).
• National Fire Protection Association, Fire protection guide on hazardous materials. 10th ed. Quincy, Mass. : NFPA. (1991). [RR-334001]   http://www.nfpa.org/
• Lenga, R.E. et Votoupal, K.L., The Sigma-Aldrich library of regulatory and safety data. Vol. 1. Milwaukee : Sigma-Aldrich. (1993). [RM-515040]
• Patty, F.A., Patty's industrial hygiene and toxicology. Vol. 2, 3rd ed. New York : John Wiley & Son. (1978).
• Bretherick, L., Bretherick's handbook of reactive chemical hazards. 4th ed. London; Toronto : Butterworth-Heinemann. (1990).
• Rickert, D.E. et al., «Hepatic macromolecular covalent binding of mononitrotoluenes in Fischer-344 rats.» Chemico-Biological Interactions. Vol. 52, p. 131-139. (1984). [AP-043950]
• Doolittle, D.J., Sherrill, J.M. et Butterworth, B.E., «Influence of intestinal bacteria, sex of the animal and position of the nitro group on the hepatic genotoxicity of nitrotoluene isomers in vivo.» Cancer Research. Vol. 43, no. 6, p. 2836-2842. (1983). [AP-043951]   http://cancerres.aacrjournals.org/content/43/6/2836.full.pdf
• Hawley, G. G., Sax, N. I. et Lewis, R. J., Hawley's condensed chemical dictionary. 11th ed. rev. New York : Van Nostrand Reinhold. (1987). [RS-407001]   http://onlinelibrary.wiley.com/book/10.1002/9780470114735 
• Document effacé.
• National Institute for Occupational Safety and Health et États-Unis. Occupational Safety and Health Administration, Occupational health guidelines for chemical hazards. Vol. 1. Cincinnati : Centers for Disease Control. (1981-). DHSS-NIOSH 81-123. [RR-015002]   http://www.cdc.gov/niosh/docs/81-123/
• Dunnick, J.K., NTP technical report on toxicity studies of o-,m-, and p-nitrololuenes., 1992 Microfiche : PB93-150092, NIH/PUB-93-3346

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