WHMIS (n-Propyl bromide)

Workplace Hazardous Materials Information System

WHMIS 2015 classification - Note to reader

• Flammable liquids - Category 21 2 3 4
• Flash point = -10 °C Pensky-Martens closed cup and boiling point = 71 °C

• Skin corrosion/irritation - Category 25 6 7 8

• Carcinogenicity - Category 29 10 11

• Reproductive toxicity - Category 1B7 12 13
• Toxic to the reproductive function (category 1B)
• Toxic to the development (category 2)

• Specific target organ toxicity - repeated exposure - Category 17 9 14

Danger

Highly flammable liquid and vapour (H225)
Causes skin irritation (H315)
Suspected of causing cancer (H351)
May damage fertility or the unborn child (H360)
Causes damage to organs through prolonged or repeated exposure (H372)

Ingredient disclosure

References

• ▲1.  National Institute for Occupational Safety and Health, NIOSH pocket guide to chemical hazards. 3 ed. Cincinnati, Ohio : NIOSH. (2007). [RM-514001]   https://www.cdc.gov/niosh/npg/default.html
• ▲2.  European Chemicals Bureau, Summary record. Expert meeting on classification for flammability hazard . ECBI/59/02.   http://ecb.jrc.it/classlab/SummaryRecord/5902a1_sr_physchem_041202.doc
• ▲3.  Pohanish, R.P. et Greene, S.A., Hazardous materials handbook. New York (NY) : Van Nostrand Reinhold. (1996). [RR-515125]
• ▲4.  European chemicals agency, 1-bromopropane (n-propyl bromide). SVHC SUPPORT DOCUMENT. (2012).
• ▲5.  ECHA (European Chemicals Agency) , Information on Chemicals (REACH). Helsinki, Finland.  

  http://echa.europa.eu/information-on-chemicals/registered-substances
  ECHA CHEM (europa.eu)

  
  
• ▲6.  Centre canadien d'hygiène et de sécurité au travail, CHEMINFO, Hamilton, Ont. : Canadian Centre for Occupational Health and Safety   http://ccinfoweb.ccohs.ca/cheminfo/search.html
• ▲7.  France. Institut national de recherche et de sécurité, Fiche toxicologique no 250 : 1-Bromopropane. Cahiers de notes documentaires. Paris : INRS. (2018). [RE-005509]   http://www.inrs.fr/publications/bdd/fichetox.html
  http://www.inrs.fr/publications/bdd/fichetox/fiche.html?refINRS=FICHETOX_250
• ▲8.  Jacobs, G. et Martens, M., «Evaluation of the test method for skin irritation as prescribed by OECD and EEC.» Journal of Toxicology : Cutaneous and Ocular Toxicology. Vol. 6, no. 3, p. 215-225. (1987). [AP-021649]
• ▲9.  American Conference of Governmental Industrial Hygienists, Documentation of the threshold limit values and biological exposure indices / Documentation of TLV's and BEI's. 7th ed. Cincinnati, Ohio : ACGIH. (2001-). Publication #0100Doc. [RM-514008]   http://www.acgih.org
• ▲10.  National toxicology Program, 13th Report on Carcinogens: 1-Bromopropane. (2014).   http://ntp.niehs.nih.gov/ntp/roc/content/profiles/bromopropane.pdf
• ▲11.  IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, Some Industrial Chemicals. IARC monographs on the evaluation of carcinogenic risks to humans, Vol. 115. Lyon : International Agency for Research on Cancer. (2018).   http://monographs.iarc.fr/
  http://monographs.iarc.fr/ENG/Monographs/vol115/index.php
• ▲12.  INRS, DEMETER : documents pour l'évaluation médicale des produits toxiques vis-à-vis de la reproduction. Paris : Institut national de recherche et de sécurité pour la prévention des accidents du travail et des maladies professionnelles. (2006).   http://www.inrs.fr/publications/bdd/demeter.html
• ▲13.  Center for the evaluation of risks to human reproduction (CERHR), NTP-CERHR Monograph on the Potential Human Reproductive and Developmental Effects of 1-Bromopropane. National Toxicology Program. (2003). 04-4479.   http://ntp.niehs.nih.gov/ntp/ohat/bromopropanes/1-bromopropane/1bp_monograph.pdf
• ▲14.  Ichihara G. et al., «Neurological Disorders in Three Workers Exposed to 1-Bromopropane.» Journal of Occupational Health. Vol. 44, p. 1-7. (2002).

The [number] refers to the Information SST database of the CNESST Documentation Center.